Alzheimer's disease (AD) therapeutics-1: Repeated clinical failures continue to question the amyloid hypothesis of AD and the current understanding of AD causality

Mullane, K; Williams, M

Williams, M (reprint author), Ohio State Univ, Coll Med, Dept Biol Chem & Pharmacol, Columbus, OH 43210 USA.

BIOCHEMICAL PHARMACOLOGY, 2018; 158 (): 359

Abstract

Deposits of amyloid plaques and neurofibrillary tangles of aggregated tau in the brain represent key hallmarks of the neurodegenerative disorder, Alzh......

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