Effect of severe renal impairment on the pharmacokinetics of brigatinib

Gupta, N; Hanley, MJ; Kerstein, D; Tugnait, M; Narasimhan, N; Marbury, TC; Venkatakrishnan, K

Gupta, N (corresponding author), Millennium Pharmaceut Inc, 40 Landsdowne St, Cambridge, MA 02139 USA.

INVESTIGATIONAL NEW DRUGS, ; ():

Abstract

Background Brigatinib, a next-generation anaplastic lymphoma kinase (ALK) inhibitor, targets activated, mutant forms of ALK and overcomes mechanisms o......

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