Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis

Hanafin, PO; Sermet-Gaudelus, I; Griese, M; Kappler, M; Ellemunter, H; Schwarz, C; Wilson, J; Tan, M; Velkov, T; Rao, GG; Schneider-Futschik, EK

Rao, GG (corresponding author), Univ N Carolina, Div Pharmacotherapy & Expt Therapeut, UNC Eshelman Sch Pharm, Chapel Hill, NC 27515 USA.; Schneider-Futschik, EK (corresponding author), Univ Melbourne, Fac Med Dent & Hlth Sci, Sch Biomed Sci, Dept Biochem & Pharmacol, Parkville, Vic, Australia.

FRONTIERS IN PHARMACOLOGY, 2021; 12 ():

Abstract

Background: The advent of cystic fibrosis transmembrane conductance regulator protein (CFTR) modulators like ivacaftor have revolutionised the treatme......

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