Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis

Yang, F; Su, WJ; Chung, OW; Tracy, L; Wang, L; Ramsden, DA; Zhang, ZZ

Zhang, ZZ (通讯作者)，Duke Univ, Sch Med, Dept Pharmacol & Canc Biol, Durham, NC 27710 USA.;Zhang, ZZ (通讯作者)，Duke Univ, Sch Med, Duke Regenerat Ctr, Durham, NC 27710 USA.

NATURE, 2023; 620 (7972): 218

Abstract

Retrotransposons are highly enriched in the animal genome(1-3). The activation of retrotransposons can rewrite host DNA information and fundamentally ......

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