Molecular mechanism of point mutation-induced Monopolar spindle 1 (Mps1/TTK) inhibitor resistance revealed by a comprehensive molecular modeling study

Han, Y; Wu, YG; Xu, Y; Guo, WT; Zhang, N; Wang, XY

Han, Y (reprint author), Wenzhou Med Univ, Affiliated Hosp 1, Dept TCM Orthoped & Traumatol, Wenzhou, Zhejiang, Peoples R China.

PEERJ, 2019; 7 ():

Abstract

Background. Monopolar spindle 1 (Mps1/TTK) is an apical dual-specificity protein kinase in the spindle assembly checkpoint (SAC) that guarantees accur......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索