W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319

Zhong, L; Liu, Q; Liu, QF; Zhang, SK; Cao, YB; Yang, DH; Wang, MW

Yang, DH; Wang, MW (corresponding author), Chinese Acad Sci, Natl Ctr Drug Screening, CAS Key Lab Receptor Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China.

CHEMICAL BIOLOGY & DRUG DESIGN, 2021; 97 (5): 1089

Abstract

Thioredoxin-interacting protein (TXNIP) overexpression is implicated in the pathogenesis of type 2 diabetes. Previous studies have shown that a small ......

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