Lineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigm

Strasser, MK; Hoppe, PS; Loeffler, D; Kokkaliaris, KD; Schroeder, T; Theis, FJ; Marr, C

Marr, C (reprint author), Helmholtz Zentrum Munchen, Inst Computat Biol, D-85764 Neuherberg, Germany.; Schroeder, T (reprint author), Swiss Fed Inst Technol, Dept Biosyst Sci & Engn DBSSE, CH-4058 Basel, Switzerland.

NATURE COMMUNICATIONS, 2018; 9 ():

Abstract

Molecular regulation of cell fate decisions underlies health and disease. To identify molecules that are active or regulated during a decision, and no......

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