Single domain based bispecific antibody, Muc1-Bi-1, and its humanized form, Muc1-Bi-2, induce potent cancer cell killing in muc1 positive tumor cells-MedSci.cn

Single domain based bispecific antibody, Muc1-Bi-1, and its humanized form, Muc1-Bi-2, induce potent cancer cell killing in muc1 positive tumor cells

Li, YM; Zhou, CH; Li, J; Liu, JY; Lin, LM; Li, L; Cao, DL; Li, Q; Wang, Z

Li, Q; Wang, Z (reprint author), Sch Pharmaceut Sci, Guangzhou, Guangdong, Peoples R China.; Li, Q; Wang, Z (reprint author), Sun Yat Sen Univ, Ctr Cellular & Struct Biol, Guangzhou, Guangdong, Peoples R China.

PLOS ONE, 2018; 13 (1):

Abstract

Muc1 is one of the most studied tumor antigens. However, antibodies or antibody-toxin conjugates against Muc1 have not shown significant efficacy for ......

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Single domain based bispecific antibody, Muc1-Bi-1, and its humanized form, Muc1-Bi-2, induce potent cancer cell killing in muc1 positive tumor cells

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