Selective Downregulation of JAK2 and JAK3 by an ATP-Competitive pan-JAK Inhibitor

Field, SD; Arkin, J; Li, J; Jones, LH

Li, J; Jones, LH (reprint author), Pfizer, Med Design, 610 Main St, Cambridge, MA 02139 USA.

ACS CHEMICAL BIOLOGY, 2017; 12 (5): 1183

Abstract

PF-956980 has been used previously as a JAK3-selective chemical probe in numerous cell-based experiments. Here, we report that not only is PF-956980 a......

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