Identification of Novel Cyclin A2 Binding site and Nanomolar Inhibitors of Cyclin A2-CDK2 Complex

Kim, SS; Alves, MJ; Gygli, P; Otero, J; Lindert, S

Otero, J; Lindert, S (corresponding author), Ohio State Univ, Dept Chem & Biochem, Columbus, OH 43210 USA.

CURRENT COMPUTER-AIDED DRUG DESIGN, 2021; 17 (1): 57

Abstract

Background: Given the diverse roles of cyclin A2 both in cell cycle regulation and in DNA damage response, identifying small molecule regulators of cy......

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