CD30-Positive Extracellular Vesicles Enable the Targeting of CD30-Negative DLBCL Cells by the CD30 Antibody-Drug Conjugate Brentuximab Vedotin

Lobastova, L; Lettau, M; Babatz, F; de Oliveira, TD; Nguyen, PH; Pauletti, BA; Schauss, AC; Durkop, H; Janssen, O; Leme, AFP; Hallek, M; Hansen, HP

Hansen, HP (corresponding author), Univ Cologne, Dept Internal Med 1, Cologne, Germany.; Hansen, HP (corresponding author), Ctr Integrated Oncol Aachen Bonn Cologne Duesseld, Cologne, Germany.; Hansen, HP (corresponding author), Univ Cologne, Ctr Mol Med Cologne, Cologne, Germany.; Hansen, HP (corresponding author), CECAD Ctr Excellence Cellular Str Responses Aging, Cologne, Germany.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021; 9 ():

Abstract

CD30, a member of the TNF receptor superfamily, is selectively expressed on a subset of activated lymphocytes and on malignant cells of certain lympho......

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