The magnitude of ivacaftor effects on fluid secretion via R117H-CFTR channels: Human in vivo measurements

Char, JE; Dunn, C; Davies, Z; Milla, C; Moss, RB; Wine, JJ

Wine, JJ (reprint author), Stanford Univ, Cyst Fibrosis Res Lab, Stanford, CA 94305 USA.; Wine, JJ (reprint author), Stanford Univ, Dept Pediat, Sch Med, Stanford, CA 94305 USA.

PLOS ONE, 2017; 12 (4):

Abstract

We optically measured effects of orally available ivacaftor (Kalydeco (R)) on sweat rates of identified glands in 3 R117H subjects, each having a uniq......

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