Combining IL-2-based immunotherapy with commensal probiotics produces enhanced antitumor immune response and tumor clearance

Shi, LL; Sheng, JY; Chen, GZ; Zhu, P; Shi, CP; Li, B; Park, C; Wang, JY; Zhang, BX; Liu, Z; Yang, XL

Yang, XL (corresponding author), Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Natl Engn Res Ctr Nanomed, Wuhan, Peoples R China.; Liu, Z (corresponding author), Huazhong Univ Sci & Technol, Dept Biotechnol, Coll Life Sci & Technol, Wuhan, Peoples R China.; Zhang, BX (corresponding author), Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Hepat Surg Ctr, Wuhan, Peoples R China.

JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020; 8 (2):

Abstract

Background Interleukin-2 (IL-2) serves as a pioneer of immunotherapeutic agent in cancer treatment. However, there is a considerable proportion of pat......

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