CXCL4 drives fibrosis by promoting several key cellular and molecular processes

Affandi, AJ; Carvalheiro, T; Ottria, A; de Haan, JJ; Brans, MAD; Brandt, MM; Tieland, RG; Lopes, AP; Fernandez, BM; Bekker, CPJ; van der Linden, M; Zimmermann, M; Giovannone, B; Wichers, CGK; Garcia, S; de Kok, M; Stifano, G; Xu, YJ; Kowalska, MA; Waasdorp, M; Cheng, C; Gibbs, S; de Jager, SCA; van Roon, JAG; Radstake, TRDJ; Marut, W

Marut, W (通讯作者)，Univ Utrecht, Univ Med Ctr Utrecht, Ctr Translat Immunol, Utrecht, Netherlands.;Marut, W (通讯作者)，Univ Utrecht, Univ Med Ctr Utrecht, Dept Rheumatol & Clin Immunol, Utrecht, Netherlands.

CELL REPORTS, 2022; 38 (1):

Abstract

Fibrosis is a major cause of mortality worldwide, characterized by myofibroblast activation and excessive extracellular matrix deposition. Systemic sc......

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