Cytosolic and mitochondrial tRNA synthetase inhibitors increase lifespan in a GCN4/atf-4-dependent manner

Robbins, CE; Patel, B; Sawyer, DL; Wilkinson, B; Kennedy, BK; McCormick, MA

McCormick, MA (通讯作者),Univ New Mexico, Sch Med, Dept Biochem & Mol Biol, Hlth Sci Ctr, Albuquerque, NM 87131 USA.;McCormick, MA (通讯作者),Buck Inst Res Aging, Novato, CA 94945 USA.;Kennedy, BK (通讯作者),Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Biochem & Physiol, Singapore 119077, Singapore.;McCormick, MA (通讯作者),Autophagy Inflammat & Metab Ctr Biomed Res Excelle, Albuquerque, NM 87131 USA.

ISCIENCE, 2022; 25 (11):