Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines

Zhang, L; Li, J; Hu, J; Li, DD; Wang, XH; Zhang, R; Zhang, H; Shi, M; Chen, H

Chen, H (reprint author), Chongqing Med Univ, Dept Resp & Crit Care Med, Affiliated Hosp 1, 1 Yixue Rd, Chongqing 400016, Peoples R China.

LUNG CANCER, 2017; 109 ( ): 109

Abstract

Objectives: Epithelial growth factor receptor (EGFR) somatic-mutated non-small cell lung cancer (NSCLC) patients with smoking history always show a po......

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