IL-23-producing IL-10R alpha-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response

Bernshtein, B; Curato, C; Ioannou, M; Thaiss, CA; Gross-Vered, M; Kolesnikov, M; Wang, Q; David, E; Chappell-Maor, L; Harmelin, A; Elinav, E; Thakker, P; Papayannopoulos, V; Jung, S

Jung, S (reprint author), Weizmann Inst Sci, Dept Immunol, IL-76100 Rehovot, Israel.

SCIENCE IMMUNOLOGY, 2019; 4 (36):

Abstract

Cytokines maintain intestinal health, but precise intercellular communication networks remain poorly understood. Macrophages are immune sentinels of t......

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