Design, synthesis, and LFA-1/ICAM-1 antagonist activity evaluation of Lifitegrast analogues

Du, GX; Du, WW; An, YL; Wang, MN; Hao, FF; Tong, XC; Gong, Q; He, XD; Jiang, HL; He, W; Zheng, MY; Zhang, DL

Zhang, DL (通讯作者)，He Univ, Sch Pharm, Shenyang 110163, Peoples R China.;Zhang, DL (通讯作者)，Shenyang Ind Technol Inst Ophthalmol, Shenyang 110163, Peoples R China.;Zheng, MY (通讯作者)，Chinese Acad Sci, Drug Discovery & Design Ctr, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China.

MEDICINAL CHEMISTRY RESEARCH, 2022; 31 (4): 555

Abstract

The interaction between Lymphocyte function-associated antigen 1 (LFA-1) and intercellular-adhesion molecule-1 (ICAM-1) plays important roles in the c......

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