A Streamlined, Green, and Sustainable Synthesis of the Anticancer Agent Erdafitinib

Singhania, V; Nelson, CB; Reamey, M; Morin, E; Kavthe, RD; Lipshutz, BH

Lipshutz, BH (通讯作者),Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA.

ORGANIC LETTERS, 2023; 25 (23): 4308

Abstract

Erdafitinib, an anticancer drug, was synthesized in athree-steptwo-pot sequence involving ppm levels of Pd catalyst run under aqueousmicellar conditio......

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