Pharmacokinetics of Daprodustat and Metabolites in Individuals with Normal and Impaired Hepatic Function

Mahar, KM; Shaddinger, BC; Ramanjineyulu, B; Andrews, S; Caltabiano, S; Lindsay, AC; Cobitz, AR

Mahar, KM (通讯作者),Clin Pharmacol Modeling & Simulat, 1250 S Collegeville Rd,MS UP4200, Collegeville, PA 19426 USA.

CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2022; 11 (5): 562

Abstract

Daprodustat is a hypoxia-inducible factor-prolyl hydroxylase inhibitor in development for treatment of anemia of chronic kidney disease. We evaluated ......

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