CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches

Argiriadi, MA; Benatuil, L; Dubrovska, I; Egan, DA; Gao, L; Greischar, A; Hardman, J; Harlan, J; Iyer, RB; Judge, RA; Lake, M; Perron, DC; Sadhukhan, R; Sielaff, B; Sousa, S; Wang, R; McRae, BL

Argiriadi, MA (reprint author), AbbVie Biores Ctr, 381 Plantat St, Worcester, MA 01605 USA.

BMC MOLECULAR AND CELL BIOLOGY, 2019; 20 (1):

Abstract

Background CD40 is a 48 kDa type I transmembrane protein that is constitutively expressed on hematopoietic cells such as dendritic cells, macrophages,......

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