PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers

Keung, MYT; Wu, YY; Vadgama, JV

Vadgama, JV (reprint author), Charles Drew Univ, Div Canc Res & Training, Los Angeles, CA 90059 USA.; Vadgama, JV (reprint author), Univ Calif Los Angeles, Johnsson Comprehens Canc Ctr, David Geffen Sch Med, Los Angeles, CA 90095 USA.

JOURNAL OF CLINICAL MEDICINE, 2019; 8 (4):

Abstract

Poly (ADP-ribose) polymerases (PARPs) play an important role in various cellular processes, such as replication, recombination, chromatin remodeling, ......

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