Signaling properties of murine MPL and MPL mutants after stimulation with thrombopoietin and romiplostim

Rommel, MGE; Hoerster, K; Milde, C; Schenk, F; Roser, L; Kohlscheen, S; Heinz, N; Modlich, U

Modlich, U (corresponding author), Paul Ehrlich Inst, Div Vet Med, Res Grp Gene Modificat Stem Cells, D-63225 Langen, Germany.

EXPERIMENTAL HEMATOLOGY, 2020; 85 (): 33

Abstract

Thrombopoietin (THPO) and its receptor myeloproliferative leukemia virus oncogene (MPL) regulate hematopoietic stem cell (HSC) quiescence and maintena......

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