Novel pyrrolopyrimidines as Mps1/TTK kinase inhibitors for breast cancer

Sugimoto, Y; Sawant, DB; Fisk, HA; Mao, LG; Li, CL; Chettiar, S; Li, PK; Darby, MV; Brueggemeier, RW

Brueggemeier, RW (reprint author), Ohio State Univ, Coll Pharm, Div Med Chem & Pharmacognosy, Columbus, OH 43210 USA.

BIOORGANIC & MEDICINAL CHEMISTRY, 2017; 25 (7): 2156

Abstract

New targeted therapy approaches for certain subtypes of breast cancer, such as triple-negative breast cancers and other aggressive phenotypes, are des......

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