TMBleR: a bioinformatic tool to optimize TMB estimation and predictive power

Fancello, L; Guida, A; Frige, G; Ceol, AGM; Babini, G; Scaglione, GL; Zanfardino, M; Mazza, T; Ferrando, L; Pelicci, PG; Mazzarella, L

Mazzarella, L (通讯作者)，European Inst Oncol IRCCS, IEO, Dept Expt Oncol, Milan, Italy.;Mazzarella, L (通讯作者)，European Inst Oncol IRCCS, IEO, Div Early Drug Dev, Milan, Italy.

BIOINFORMATICS, 2022; 38 (6): 1724

Abstract

Motivation Tumor mutational burden (TMB) has been proposed as a predictive biomarker for immunotherapy response in cancer patients, as it is thought t......

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