健康环境中某些特定基因可以延长寿命

2016-04-26 生物谷 生物谷

布法罗大学成瘾研究所的研究人员发现了大脑的多巴胺系统中的一个基因,它在延长寿命的过程中如何发挥重要作用:秘诀是必须在健康的环境中运动。 该研究由高级研究科学家Panayotis(Peter)k.Thanos领导,相关文章发表在在线版本《Oncotarget Aging》上。 Thanos和他的研究小组研究了多巴胺基因,为了评估其对小鼠寿命和行为的影响。多巴胺是一种神经递质,用来帮助控制大脑

布法罗大学成瘾研究所的研究人员发现了大脑的多巴胺系统中的一个基因,它在延长寿命的过程中如何发挥重要作用:秘诀是必须在健康的环境中运动。

该研究由高级研究科学家Panayotis(Peter)k.Thanos领导,相关文章发表在在线版本《Oncotarget Aging》上。

Thanos和他的研究小组研究了多巴胺基因,为了评估其对小鼠寿命和行为的影响。多巴胺是一种神经递质,用来帮助控制大脑的感觉,并且帮助调节身体灵活性和情绪反应。

研究人员发现,只有加上一个健康的环境,包括社会交往,感觉和认知刺激,最关键的是运动时,多巴胺D2受体基因(D2R)才会明显影响寿命,体重和运动活性。

“运动是健康环境的一个重要组成部分,它的好处已经被证明是大脑功能和行为的强大的中间媒介。”Thanos说。

据D2R表达水平发现,在良好的环境下生存的小鼠比在恶劣环境中生存的小鼠的寿命长16%-22%。

“这些结果首次提供了证据证明D2R基因-环境相互作用对长寿和衰老起着重要的作用。”Thanos说。“关于解密长寿的个体差异 ,研究者针对基因和环境的二分法提供了一个严格的和长期的辩论。事实上,它们之间存在着复杂的相互作用。”

研究探索这种基因-环境交互作用应该促使人们更好地了解和预测特定环境的潜在好处,比如锻炼对老年人健康长寿的作用。

原始出处:

Research shows certain genes, in healthy environments, can lengthen lifespan


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    2016-08-29 ylzr123

    深入学习,好文值得点赞!

    0

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    2016-04-27 1de11f7fm56(暂无匿称)

    学习了一下新知识

    0

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    2016-04-27 老段

    寿命是一个综合因素作用的效果

    0

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    2016-04-27 WEIXINef251673

    我觉得应该说:健康的环境可以延长生命,或者说某某基因可以……

    0

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    2016-04-26 famous

    好的很

    0