J Endod:根管封闭剂对浮游细菌和菌斑生物膜的抗菌活性

2017-11-22 lishiting MedSci原创

这篇研究的目的是为了评估4种根管封闭剂对浮游细菌的生长或在持久性和继发性牙髓感染中常见的菌斑生物膜的抗菌活性。

这篇研究的目的是为了评估4种根管封闭剂对浮游细菌的生长或在持久性和继发性牙髓感染中常见的菌斑生物膜的抗菌活性。

研究通过浮游生物的生长和培养24小时的粪肠球菌、表皮葡萄球菌、金黄色葡萄球菌和变异链球菌生物膜的变化检测AH Plus, TotalFill BC sealer, RoekoSeal和Guttaflow 2的抗菌活性。

结果显示,AH Plus对所有检测的菌属均表现出较高的抗菌活性,不论浮游生物还是在菌斑生物膜内。然而,抗菌活性在24小时后消失。TotalFill BC sealer在施加后表现出对浮游细菌长达持续7天的明显抗菌效果。当封闭剂与生物膜直接接触以及对所有菌属采用薄膜将封闭剂与生物膜相分离时,TotalFill BC sealer与AH Plus相比对金黄色葡萄球菌和粪肠球菌生物膜表现出较低的抗菌活性。而Guttaflow 2和RoekoSeal对浮游细菌和菌斑生物模没有抗菌活性。

结论:施加刺激后,在最初的24小时内,与TotalFill BC相比,菌斑生物膜对AH Plus表现出更好的易感性。检测根管封闭剂和材料对菌斑生物模的抗菌活性对于评估材料清除感染根管内细菌的能力具有非常重要的作用。

原始出处

Kapralos V, Koutroulis A, et al. Antibacterial Activity of Endodontic Sealers against Planktonic Bacteria and Bacteria in Biofilms. J Endod. 2017 Nov 15. pii: S0099-2399(17)30975-5. doi: 10.1016/j.joen.2017.08.023.

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    2018-04-17 wrj0131
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    2017-12-07 120ecc2bm88暂无昵称

    谢谢分享!

    0

  4. 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    2017-11-25 Drhzm308

    呵呵.学习了

    0

  5. 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  6. 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GetPortalCommentsPageByObjectIdResponse(id=263515, encodeId=1a3f26351502, content=不错的分享.谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/b594a756d77e4171b5313e531ef89b43/31c000a8a97d4872b698c80fb8a33369.jpg, createdBy=624b2152505, createdName=大叔默默路过, createdTime=Thu Nov 23 06:57:34 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1694333, encodeId=e57e1694333b4, content=<a href='/topic/show?id=9b558805847' target=_blank style='color:#2F92EE;'>#菌斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88058, encryptionId=9b558805847, topicName=菌斑)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a9729602115, createdName=wrj0131, createdTime=Tue Apr 17 06:48:00 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061231, encodeId=ac562061231a7, content=<a href='/topic/show?id=5bd4622567b' target=_blank style='color:#2F92EE;'>#根管封闭剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62256, encryptionId=5bd4622567b, topicName=根管封闭剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d64f419, 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GetPortalCommentsPageByObjectIdResponse(id=263515, encodeId=1a3f26351502, content=不错的分享.谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/b594a756d77e4171b5313e531ef89b43/31c000a8a97d4872b698c80fb8a33369.jpg, createdBy=624b2152505, createdName=大叔默默路过, createdTime=Thu Nov 23 06:57:34 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=1694333, encodeId=e57e1694333b4, content=<a href='/topic/show?id=9b558805847' target=_blank style='color:#2F92EE;'>#菌斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88058, encryptionId=9b558805847, topicName=菌斑)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a9729602115, createdName=wrj0131, createdTime=Tue Apr 17 06:48:00 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061231, encodeId=ac562061231a7, content=<a href='/topic/show?id=5bd4622567b' target=_blank style='color:#2F92EE;'>#根管封闭剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62256, encryptionId=5bd4622567b, topicName=根管封闭剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d64f419, 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time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1330625, encodeId=932413306259d, content=<a href='/topic/show?id=c6b455688d1' target=_blank style='color:#2F92EE;'>#抗菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55688, encryptionId=c6b455688d1, topicName=抗菌)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/2898B09F0DA89357D0D54A725E611AC7/100, createdBy=fdd32500040, createdName=ms7899726347904398, createdTime=Fri Nov 24 13:48:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1443037, encodeId=f06b144303ed4, content=<a href='/topic/show?id=674546e8323' target=_blank style='color:#2F92EE;'>#封闭剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46783, encryptionId=674546e8323, topicName=封闭剂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b88a5021004, createdName=12498dd9m12暂无昵称, createdTime=Fri Nov 24 13:48:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522860, encodeId=c0d81522860c2, content=<a href='/topic/show?id=c72462241ff' target=_blank style='color:#2F92EE;'>#根管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62241, encryptionId=c72462241ff, topicName=根管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5e11492705, createdName=zhaozhouchifen, createdTime=Fri Nov 24 13:48:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538714, encodeId=58c41538e1496, content=<a href='/topic/show?id=35fa55e03ee' target=_blank style='color:#2F92EE;'>#抗菌活性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55703, encryptionId=35fa55e03ee, topicName=抗菌活性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fe6d13029843, createdName=xre2012, createdTime=Fri Nov 24 13:48:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263538, encodeId=501b263538dd, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Nov 23 07:45:22 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263515, encodeId=1a3f26351502, content=不错的分享.谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/b594a756d77e4171b5313e531ef89b43/31c000a8a97d4872b698c80fb8a33369.jpg, createdBy=624b2152505, createdName=大叔默默路过, createdTime=Thu Nov 23 06:57:34 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 清风拂面

    谢谢分享.学习了

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1694333, encodeId=e57e1694333b4, content=<a href='/topic/show?id=9b558805847' target=_blank style='color:#2F92EE;'>#菌斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88058, encryptionId=9b558805847, topicName=菌斑)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a9729602115, createdName=wrj0131, createdTime=Tue Apr 17 06:48:00 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061231, encodeId=ac562061231a7, content=<a href='/topic/show?id=5bd4622567b' target=_blank style='color:#2F92EE;'>#根管封闭剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62256, encryptionId=5bd4622567b, topicName=根管封闭剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d64f419, 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time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1330625, encodeId=932413306259d, content=<a href='/topic/show?id=c6b455688d1' target=_blank style='color:#2F92EE;'>#抗菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55688, encryptionId=c6b455688d1, topicName=抗菌)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/2898B09F0DA89357D0D54A725E611AC7/100, createdBy=fdd32500040, createdName=ms7899726347904398, createdTime=Fri Nov 24 13:48:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1443037, encodeId=f06b144303ed4, content=<a href='/topic/show?id=674546e8323' target=_blank style='color:#2F92EE;'>#封闭剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46783, encryptionId=674546e8323, topicName=封闭剂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b88a5021004, createdName=12498dd9m12暂无昵称, createdTime=Fri Nov 24 13:48:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522860, encodeId=c0d81522860c2, content=<a href='/topic/show?id=c72462241ff' target=_blank style='color:#2F92EE;'>#根管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62241, encryptionId=c72462241ff, topicName=根管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5e11492705, createdName=zhaozhouchifen, createdTime=Fri Nov 24 13:48:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538714, encodeId=58c41538e1496, content=<a href='/topic/show?id=35fa55e03ee' target=_blank 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GetPortalCommentsPageByObjectIdResponse(id=263515, encodeId=1a3f26351502, content=不错的分享.谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/b594a756d77e4171b5313e531ef89b43/31c000a8a97d4872b698c80fb8a33369.jpg, createdBy=624b2152505, createdName=大叔默默路过, createdTime=Thu Nov 23 06:57:34 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 大叔默默路过

    不错的分享.谢谢

    0

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目前临床上拥有多种牙髓封闭剂材料,但对理想封闭剂的探索却从未停止过。这篇研究的目的是评估一种含有氢氧化钙的新型环氧树脂类牙髓封闭剂-Sealer Plus的细胞毒性和生物相容性。AH Plus, Endofill和SimpliSeal牙髓封闭剂用来做对照。