Colorectal Dis:T1期直肠癌经肛门内镜显微手术后复发率研究

2018-07-13 zhangfan MedSci原创

研究发现,T1期直肠癌患者接受肛门内镜显微局部切除手术后局部复发率较低,有效的术前评估、局部切除手术并联合术后放疗可进一步的改善早期直肠癌患者预后

近年来微创器官保留手术在早期直肠癌中的应用越来越多,然而局部复发仍然是微创手术难以回避的问题。近日研究人员就单一医疗中心10年中T1直肠癌局部切除术后的复发率进行了考察。

研究在英国开展,该中心10年间所有接受经肛门内镜显微局部切除手术(TEM)的T1期直肠癌患者参与,主要终点为局部复发率。

总计192名患者接受TEM直肠癌手术,其中70人经病理检查确诊为T1期直肠癌且患者术前未接受放疗。70名患者中,10人接受了术后放疗,其他60名患者中,6人发生局部复发,3人接受后续手术,TEM术后3年的累积复发率为7.2%。

研究发现,T1期直肠癌患者接受肛门内镜显微局部切除手术后局部复发率较低,有效的术前评估、局部切除手术并联合术后放疗可进一步的改善早期直肠癌患者预后。

原始出处:


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    2018-10-20 shalley66
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    2018-10-20 windight
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  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391758, encodeId=11d21391e58d2, content=<a href='/topic/show?id=eb615005c7' target=_blank style='color:#2F92EE;'>#Colorectal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5005, encryptionId=eb615005c7, topicName=Colorectal)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/JicbM9ddhTaNkKdhKQ8adCYWzVJQKZXsqSTg3ia12tmdibiaoTZTEjBqfVvmfODz1KpD73pKy4h1W0fAXj62kxGbQA/132, createdBy=d2132500095, createdName=ms5768352621950538, createdTime=Sat Jul 14 21:38:00 CST 2018, time=2018-07-14, status=1, ipAttribution=)]
  6. 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channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81144, encryptionId=c8168114412, topicName=肛门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=39bc29444908, createdName=hxj0127, createdTime=Thu Aug 02 16:38:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012743, encodeId=7c092012e43b3, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sat Aug 18 04:38:00 CST 2018, time=2018-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=331880, encodeId=c4a93318809d, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Mon Jul 16 00:27:19 CST 2018, time=2018-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1261997, encodeId=3658126199e80, content=<a href='/topic/show?id=0ceb30545e0' target=_blank style='color:#2F92EE;'>#内镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30545, encryptionId=0ceb30545e0, topicName=内镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sat Jul 14 21:38:00 CST 2018, time=2018-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391758, encodeId=11d21391e58d2, content=<a href='/topic/show?id=eb615005c7' target=_blank style='color:#2F92EE;'>#Colorectal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5005, encryptionId=eb615005c7, topicName=Colorectal)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/JicbM9ddhTaNkKdhKQ8adCYWzVJQKZXsqSTg3ia12tmdibiaoTZTEjBqfVvmfODz1KpD73pKy4h1W0fAXj62kxGbQA/132, createdBy=d2132500095, createdName=ms5768352621950538, createdTime=Sat Jul 14 21:38:00 CST 2018, time=2018-07-14, status=1, ipAttribution=)]
    2018-08-02 hxj0127
  7. 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  8. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391758, encodeId=11d21391e58d2, content=<a href='/topic/show?id=eb615005c7' target=_blank style='color:#2F92EE;'>#Colorectal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5005, encryptionId=eb615005c7, topicName=Colorectal)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/JicbM9ddhTaNkKdhKQ8adCYWzVJQKZXsqSTg3ia12tmdibiaoTZTEjBqfVvmfODz1KpD73pKy4h1W0fAXj62kxGbQA/132, createdBy=d2132500095, createdName=ms5768352621950538, createdTime=Sat Jul 14 21:38:00 CST 2018, time=2018-07-14, status=1, ipAttribution=)]
    2018-07-16 jihuaijun1112

    学习学习学习

    0

  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1391758, encodeId=11d21391e58d2, content=<a href='/topic/show?id=eb615005c7' target=_blank style='color:#2F92EE;'>#Colorectal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5005, encryptionId=eb615005c7, topicName=Colorectal)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/JicbM9ddhTaNkKdhKQ8adCYWzVJQKZXsqSTg3ia12tmdibiaoTZTEjBqfVvmfODz1KpD73pKy4h1W0fAXj62kxGbQA/132, createdBy=d2132500095, createdName=ms5768352621950538, createdTime=Sat Jul 14 21:38:00 CST 2018, time=2018-07-14, status=1, ipAttribution=)]
    2018-07-14 docwu2019
  10. 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NCCN临床实践指南:直肠癌(2018.V2)

2018年6月,美国国家综合癌症网络(NCCN)发布了直肠癌指南2018年第2版,指南主要内容涉及: 指南更新摘要 临床表现和主要治疗 监测 复发和检查 病理检查原则 手术治疗原则 辅助治疗原则 放射治疗原则 晚期或转移性疾病化疗 生存原则 分期

Gastroenterology:香港中文大学科学家发现,血液中有这几种菌,患结直肠癌风险**可增加16倍

来自香港中文大学的研究人员却想,如果它们出现在血液中,会不会也增加结直肠癌的风险呢?在不久前的《胃肠病学》(Gastroenterology)杂志中,他们给出了答案:会的!而且还会增加很多!

世界首例!用“猪小肠”修补人肠

7 月 11 日,中山大学附属第六医院肛肠外科任东林教授团队宣布,他们首次运用来源于“猪小肠”的生物补片材料,为一女性患者“修补”了直肠中的“破洞”,使直肠功能在经历 11 年的“折腾”后恢复正常。据悉,“猪小肠”生物补片运用在人体直肠重建,尚属世界首例。

JAMA Oncol:管住嘴 促炎饮食增加结直肠癌风险

2018年3月,发表在《JAMA Oncol》的一项由美国和中国科学家进行的研究,考察了促炎性饮食与结直肠癌发生风险之间的相关性。

2017 SAR建议:直肠癌患者MRI检查

2018年5月,腹部放射学会(SAR)直肠疾病工作小组发布了直肠癌患者MRI检查检查建议,本文主要针对直肠癌患者MRI检查恶相关内容提出专家建议,涉及MRI检查技术性能,说明以及检查报告的相关内容。  

Radiology:晚期直肠癌新辅助放化疗后有没有疗效呢?

本研究旨在利用MRI表观扩散系数(ADC)图分析评价局灶性晚期直肠癌(LARC)新辅助放化疗后反应的价值,并将结果发表在Radiology上。