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J Hypertens：肾动脉狭窄和左心室肥厚有啥关系？

2017-08-13 xing.T MedSci原创

肾动脉狭窄左心室肥厚血运重建
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该荟萃分析表明与高血压患者相比，RAS患者左心室肥厚的可能性增加，肾动脉血运重建对左心室结构具有有益的效应，是通过左心室重量指数显著降低来反映。

肾动脉狭窄（RAS）患者左心室肥厚（LVH）以及肾血管重建术后LVH消退的数据资料很少。近日，高血压领域权威杂志Journal of Hypertension上发表了一篇荟萃分析文章，研究人员进行了一项荟萃分析以提供关于这个临床相关问题的全面信息。

研究人员纳入了所有RAS患者通过超声心动图对LVH进行评估并与原发性高血压患者进行比较的文献，研究人员对肾动脉血管重建后左室（LV）质量指数的变化进行了评估。

该荟萃分析共纳入了905名研究参与者（RAS为446人，原发性高血压患者为459人），共纳入了九项研究。RAS患者合并的左室质量指数明显高于原发性高血压患者（140.4±11.1克/平方米和121.8±6.2克/平方米，标准差为0.41±0.07 [95%可信区间（CI）为0.27-0.51，P＜0.001]。在来自于八个研究中的360名接受了肾动脉重建的RAS患者中，基线和干预后合并的平均左室质量指数值分别为129±10.2克/平方米和115.5±9.9克/平方米，标准平均差为-0.36±-0.06（95%CI为-0.47至-0.25，P＜0.001）。这些发现不受发表偏倚或单一研究效应的影响。

由此可见，该荟萃分析表明与高血压患者相比，RAS患者左心室肥厚的可能性增加，肾动脉血运重建对左心室结构具有有益的效应，是通过左心室重量指数显著降低来反映。

原始出处：

Cuspidi, Cesare,et al. Renal artery stenosis and left ventricular hypertrophy: an updated review and meta-analysis of echocardiographic studies.Journal of Hypertension. 2017. http://journals.lww.com/jhypertension/Abstract/publishahead/Renal_artery_stenosis_and_left_ventricular.97654.aspx

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    2018-01-15 12498ebem19暂无昵称

    #TENS#

    0

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    2017-10-27 zll0632

    #左心室肥厚#

    0

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    2018-04-18 feather89

    #PE#

    0

  4. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413201, encodeId=bf9514132015f, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Tue Aug 15 05:54:00 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-10-30 wjcjjian

    #心室肥厚#

    0

  5. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413201, encodeId=bf9514132015f, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Tue Aug 15 05:54:00 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2018-01-30 江川靖瑶

    #肾动脉#

    0

  6. 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content=谢谢分享.学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Mon Aug 21 19:33:15 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233729, encodeId=1ea1233e29a3, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Aug 15 08:29:44 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413201, encodeId=bf9514132015f, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Tue Aug 15 05:54:00 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-11-25 rgjl

    #肾动脉狭窄#

    0

  7. 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content=谢谢分享.学习了很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Mon Aug 21 19:33:15 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233729, encodeId=1ea1233e29a3, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Aug 15 08:29:44 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413201, encodeId=bf9514132015f, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Tue Aug 15 05:54:00 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-27 虈亣靌

    继续学习中谢谢

    0

  8. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413201, encodeId=bf9514132015f, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Tue Aug 15 05:54:00 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-21 虈亣靌

    谢谢分享.学习了很好!

    0

  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413201, encodeId=bf9514132015f, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Tue Aug 15 05:54:00 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-15 ylzr123

    认真学习，不断进步，把经验分享给同好。点赞了！

    0

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    2017-08-15 wushaoling

    #左心室#

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