Anal Chem:又一款无创血糖监测装置问世

2015-01-23 MedSci MedSci原创

  对于许多糖尿病患者来说,他们需要扎手指抽血来测试自己的血糖信息,这的确挺痛苦的。但是长久以来,医疗界的专业人士都没有找到一种可靠,并能够减轻患者痛苦的方法,帮助他们收集血糖数据。 去年,Google宣布他们开发了一款隐型眼镜,可以测试用户眼泪中的血糖水平。但现在,纳米工程师们找到了一种更简单的方法,可以帮助糖尿病患者监测体内血糖指标,它是一款“临时纹身”。 Amay

 54b938a62c69c.jpg

对于许多糖尿病患者来说,他们需要扎手指抽血来测试自己的血糖信息,这的确挺痛苦的。但是长久以来,医疗界的专业人士都没有找到一种可靠,并能够减轻患者痛苦的方法,帮助他们收集血糖数据。

去年,Google宣布他们开发了一款隐型眼镜,可以测试用户眼泪中的血糖水平。但现在,纳米工程师们找到了一种更简单的方法,可以帮助糖尿病患者监测体内血糖指标,它是一款“临时纹身”。

Amay Bandokar是加州大学圣迭戈分校的一名研究人员,她已经开发出了一款弹性传感器,使用微电流来测量人体内的血糖水平。对于糖尿病患者来说,一天多次测量自身的血糖水平是非常重要的,因为这可以显示出他们的身体是如何管理糖尿病,以及需要多少胰岛素剂量。过去人们需要扎针取血,但针头总是让人感到不快,所以患者通常不会每天多次测量自己的血糖水平,这也让他们处于风险之中,因为糖尿病往往会引起多种并发症。

这款设备测血糖的时候是无痛的,它的电极粘贴在一张很薄的纹身纸上面,患者使用完之后直接扔掉就可以了。“现在,这款纹身传感器的使用时间是一整天,”Bandodkar在一份申明中说道,“而且它的价格也不贵,只需几美分而已,因此对患者来说也不会有任何经济压力。”

通过一些健康人士的临床试验结果显示,这款纹身可以提供准确的血糖指标测试,该研究团队也把自己的研究成果发表在了《分析化学》期刊上。这项试验对象全部都是年龄在20到40岁之间的非糖尿病患者,他们在吃三明治喝苏打水之前,会带上这款纹身传感器。不仅如此,每次饭后这款纹身还会记录患者的血糖最高值,而测量结果则和传统的抽血设备测出的一样准确。

但是这款纹身还有一些不太方便的地方,当它还无法提供血糖数据值,科学家要将它取下,分析之后,才能得到测量值。不过根据Bandodkar透露,这款纹身很快会支持蓝牙功能,这样相关数据不仅能实时发送给患者的主治医生,而且还能再云端存储。

未来,研究人员希望这款纹身传感器设备还能监测血液中的其他指标,比如代谢产物,药物,或是酒精和毒品含量。当然,不管做什么应用,妈妈再也不用担心我在手指上扎针抽血啦。

原始出处:

Bandodkar AJ, Jia W, Yardımcı C, Wang X, Ramirez J, Wang J.Tattoo-Based Noninvasive Glucose Monitoring: A Proof-of-Concept Study. Anal Chem. 2015 Jan 6;87(1):394-8.

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    2015-04-11 x35042875

    AKI对心衰临床治疗意义重大,但依然需要研究检验其适用性

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=20418, encodeId=bc452041839, content=AKI对心衰临床治疗意义重大,但依然需要研究检验其适用性, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 22:51:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633314, encodeId=eb76163331411, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Wed Feb 04 01:37:00 CST 2015, time=2015-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700009, encodeId=9a951e000095f, content=<a href='/topic/show?id=295524e541' target=_blank style='color:#2F92EE;'>#Anal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2475, encryptionId=295524e541, topicName=Anal)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3a29999500, createdName=经常头晕, createdTime=Fri Sep 25 15:37:00 CST 2015, time=2015-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540171, encodeId=407315401e1dc, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Sun Jan 25 01:37:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14603, encodeId=1a1c1460321, content=技术发展迅速, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=42.122.216.**, createdTime=Fri Jan 23 20:35:00 CST 2015, time=2015-01-23, status=1, ipAttribution=)]
    2015-02-04 AspirantSuo
  3. [GetPortalCommentsPageByObjectIdResponse(id=20418, encodeId=bc452041839, content=AKI对心衰临床治疗意义重大,但依然需要研究检验其适用性, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 22:51:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633314, encodeId=eb76163331411, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Wed Feb 04 01:37:00 CST 2015, time=2015-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700009, encodeId=9a951e000095f, content=<a href='/topic/show?id=295524e541' target=_blank style='color:#2F92EE;'>#Anal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2475, encryptionId=295524e541, topicName=Anal)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3a29999500, createdName=经常头晕, createdTime=Fri Sep 25 15:37:00 CST 2015, time=2015-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540171, encodeId=407315401e1dc, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Sun Jan 25 01:37:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14603, encodeId=1a1c1460321, content=技术发展迅速, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=42.122.216.**, createdTime=Fri Jan 23 20:35:00 CST 2015, time=2015-01-23, status=1, ipAttribution=)]
    2015-09-25 经常头晕
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  5. [GetPortalCommentsPageByObjectIdResponse(id=20418, encodeId=bc452041839, content=AKI对心衰临床治疗意义重大,但依然需要研究检验其适用性, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 22:51:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633314, encodeId=eb76163331411, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Wed Feb 04 01:37:00 CST 2015, time=2015-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700009, encodeId=9a951e000095f, content=<a href='/topic/show?id=295524e541' target=_blank style='color:#2F92EE;'>#Anal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2475, encryptionId=295524e541, topicName=Anal)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3a29999500, createdName=经常头晕, createdTime=Fri Sep 25 15:37:00 CST 2015, time=2015-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540171, encodeId=407315401e1dc, content=<a href='/topic/show?id=da548984604' target=_blank style='color:#2F92EE;'>#血糖监测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89846, encryptionId=da548984604, topicName=血糖监测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=50fd13191418, createdName=jktdtl, createdTime=Sun Jan 25 01:37:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14603, encodeId=1a1c1460321, content=技术发展迅速, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=42.122.216.**, createdTime=Fri Jan 23 20:35:00 CST 2015, time=2015-01-23, status=1, ipAttribution=)]
    2015-01-23 42.122.216.**

    技术发展迅速

    0

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无创或成为可穿戴技术一大突破点

目前的可穿戴产品有两大困境。一个是可测量的指标有限,基本集中在心跳、呼吸、睡眠等常规指标,并不能给诊断带来太大意义。另一个则是测量精确性有限,加入遇到复杂的情况比如特殊地形,用户本身有心血管疾病,数据不稳定等情况,数据无法反映最准确的身体指标,无法成为医生的参考。 未来的可穿戴设备发展的一大核心趋势可能是:无创。举个传统行业的例子来讲,无创胶囊胃镜技术Navicam作为一大技术突破,已经被上