Lancet Infect Dis:巴西孕期登革热感染与新生儿风险

2017-05-19 zhangfan MedSci原创

孕期登革热感染与新生儿早产有一定的关系,与低体重以及畸形无关

登革热是巴西的重要公共卫生问题。近日研究人员对2007至2013年间,巴西症状性登革热孕期感染与不良的分娩结果之间的关系进行研究。

研究人员对巴西国家法定传染病信息系统与新生儿信息系统数据库分析开展回顾性研究,确认登革热感染与妊娠分娩的关系并随机选择一部分新生儿作为外部参考。

研究共包含3898名登革热阳性孕妇以及3165名阴性孕妇,以及3898名新生儿。有322名(8.4%)感染阳性孕妇发生早产,而阴性孕妇中有324人(10.4%)早产(未经调整分析的相对风险,0.81,95% CI 0.70-0.93;调整后的让步比 1.26,95% CI 1.06-1.49,p=0.006),而外部参考人群的早产率为9.1%。感染阳性孕妇以及阴性孕妇发生新生儿低体重(<2500 g)的概率相近(8.3%vs9.8%,让步比1.17,95% CI 0.99-1.39)。新生儿畸形患病率也没用显著差异(0.7% vs 0.9%)。

研究认为,孕期登革热感染与新生儿早产有一定的关系,与低体重以及畸形无关。

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    2017-10-18 howi
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    2017-06-02 jyzxjiangqin

    登革热感染与新生儿风险。

    0

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    2017-05-20 大爰

    好文章学习了谢谢分享!

    0

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    2017-05-19 天涯183

    非常好的文章,很受启发,学习了

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