不错的180度大转弯——NICE支持Roche的Tecentriq用于肺癌的治疗

2018-04-09 MedSci MedSci原创

NICE现在建议国民保健服务使用罗氏的免疫疗法的Tecentriq来治疗肺癌，此前还对此持消极态度。该指南支持使用标准化疗后疾病进展的非小细胞肺癌患者使用该药物进行治疗。Tecentriq阻断PD-L1--一种在癌细胞表面发现的重要配体，可以逃避免疫系统的检测和破坏。临床资料显示，使用Tecentriq（atezolizumab）治疗的NSCLC患者的平均生存时间为13.8个月，比接受标准化疗的患

NICE现在建议国民保健服务使用罗氏的免疫疗法的Tecentriq来治疗肺癌，此前还对此持消极态度。

该指南支持使用标准化疗后疾病进展的非小细胞肺癌患者使用该药物进行治疗。

Tecentriq阻断PD-L1--一种在癌细胞表面发现的重要配体，可以逃避免疫系统的检测和破坏。

临床资料显示，使用Tecentriq（atezolizumab）治疗的NSCLC患者的平均生存时间为13.8个月，比接受标准化疗的患者长4.2个月，同时副作用也较少。

罗氏产品有限公司(Roche Products Ltd.)整合特许经营主管Simon Eayrs说："我们很高兴看到NICE修改了它的决定，这意味着患有这种恶性肿瘤的患者现在可以获得非常需要的治疗。"

"这一决定证明，当各方共同努力找到切实可行的解决方案时，患者能够获得新的创新疗法。"

英国每年诊断出超过46，000例新发肺癌，其中约87％为非小细胞肺癌。患者的预后在很大程度上是暗淡的，10年内存活率低于5％。

"但是到目前为止，英国癌症死亡的最常见原因中，肺癌仍然是一种被忽视的疾病。"Roy Castle肺癌基金会的首席执行官Paula Chadwick说。

"特别令人兴奋的是，atezolizumab适用于患有如此多种类型的非小细胞肺癌的患者。虽然尽可能地延长生命是患者的首要任务，但他们的生活质量同样重要。需要能够改善生存的治疗方法，而不会影响额外的时间。NICE的这一决定承认了这些因素，我们对此表示欢迎。"

原文出处：http：//www.pharmatimes.com/news/nice_u-turn_sees_roches_tecentriq_backed_for_lung_cancer_1230911

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2018-11-07 linlin2312

#ROC#

29 0
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2018-07-19 shock_melon

#TEC#

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2018-04-12 hanmeijinxiu

学习了.谢谢分享

56 0
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2018-04-11 fusion

#NICE#

23 0
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2018-04-11 lfyang

#Tecentriq#

36 0
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2018-04-10 明月清辉

谢谢分享.学习了

42 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 10 04:49:47 CST 2018, time=2018-04-10, status=1, ipAttribution=)]
2018-04-10 1dd8c52fm63(暂无匿称)

了解了解.学习学习

46 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 10 04:49:47 CST 2018, time=2018-04-10, status=1, ipAttribution=)]
2018-04-10 changjiu

学习一下谢谢

51 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Apr 10 04:49:47 CST 2018, time=2018-04-10, status=1, ipAttribution=)]
2018-04-10 lofter

学习了感谢分享

45 0
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2018-04-10 飛歌

学习了很有用不错

20 0