J Rheumatol:手部骨关节炎的运动:Cochrane系统评价

2017-10-23 xiangting MedSci原创

低质量的证据表明运动对手部疼痛,功能和手指关节僵硬有小到中等的益处。

这项研究旨在评估与其他干预措施(包括安慰剂或无干预)相比,手部骨关节炎(OA)患者的运动益处和危害。

使用Cochrane协作组方法进行系统评价。检索了6个电子数据库2015年9月前的文献。入选标准:比较治疗性运动与无运动,或比较不同运动方案的随机对照临床试验。主要结局:手部疼痛,手部功能,手指关节僵硬,生活质量,不良事件,以及由于不良反应而退出试验。评估了偏倚风险和证据质量。

7项试验被纳入,5项试验(n = 381)纳入合并后的分析资料。与无运动相比,低质量的证据表明,运动可以改善手OA患者的手部疼痛[5项试验,标准平均差(SMD)-0.27,95%CI -0.47至-0.07],手功能(4项试验,SMD -0.28,95 %CI -0.58-0.02),关节僵硬(4次试验,SMD -0.36,95%CI -0.58- -0.15)。1项研究(113例参与者)评估了生活质量,非常低质量的证据显示没有差异。3项研究报告了不良事件,这些事件很少见并不严重。

5项偏倚风险偏低的研究显示,低质量的证据表明运动对手部疼痛,功能和手指关节僵硬有小到中等的益处。估计影响很小,其是否代表临床上重要的变化仍存在争议。

原始出处:
Ninaosteras, Ingvild Kjeken, Geir Smedslund, et al. Exercise for Hand Osteoarthritis: A Cochrane Systematic Review. J Rheumatol. 15 October 2017

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    2018-04-27 lisa438
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    2017-10-25 lmm397
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    2017-10-25 huagfeg
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    2017-10-23 天涯183

    非常好的文章.学习了

    0

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