ARCH PATHOL LAB MED：来自中国很大的经美国病理学家认证实验室的不典型鳞状细胞的宫颈细胞学报告率和组织学随访结果

2019-06-02 不详网络

目前在中国，有关不典型鳞状细胞的未确定意义(ASC-US)和组织学发现的报告是罕见的。本研究分析ASC-US细胞学检查与高危人乳头瘤病毒(hrHPV)检测及组织病理学随访的相关性。在经美国病理学家学院认证的实验室，研究人员分析了2011年至2015年间ASC-US患者的hrHPV检测和组织学随访情况。研究人员进行了2 206 588项Papanicolaou (Pap)检测

目前在中国，有关不典型鳞状细胞的未确定意义(ASC-US)和组织学发现的报告是罕见的。

本研究分析ASC-US细胞学检查与高危人乳头瘤病毒(hrHPV)检测及组织病理学随访的相关性。

在经美国病理学家学院认证的实验室，研究人员分析了2011年至2015年间ASC-US患者的hrHPV检测和组织学随访情况。

研究人员进行了2 206 588项Papanicolaou (Pap)检测，包括1 513 265液基细胞学制剂(68.58%)和693 323项常规Pap检测(31.42%)。整体ASC-US报告率为3.77%（2 206 588例中有83 199例），其中年龄在40至49岁的女性最高。在接受ASC-US Pap和HPV检测的18574名女性中，hrHPV阳性率为34.98%(18574人中6498人)，其中30岁以下女性最高。共有6012名ASC-US Pap检查结果的妇女在6个月内进行了组织学随访;宫颈上皮内瘤变2及以上(CIN2+)检出率为7.87%(6012例中473例)。1999名ASC-US Pap和HPV检测的妇女有组织学结果。ASC-US Pap/ hpv检测结果阳性的妇女中，CIN2阳性的占13.98%(887例中124例)，明显高于ASC-US Pap/ hpv检测结果阴性的妇女中的2.84%(1022例中29例)。宫颈鳞癌的检出率为3.95%(887例中35例)，ASC-US/ hpv阳性。

研究显示，这是中国最大关于研究HPV和ASC-US患者的组织学随访的结果。ASC-US报告率、HPV阳性率和CIN2+检出率均在目前公认的基准范围内。这些发现可能有助于为更好地了解中国宫颈癌筛查的现状并未后续研究奠定基础。

原始出处：

Baowen Zheng, MD; Huaitao Yang, MD, PhD; Atypical Squamous Cells of Undetermined Significance Cervical Cytology Report Rate and Histologic Follow-up Findings From the Largest College of American Pathologists–Certified Laboratory in China

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2019-12-23 bnurmamat

#组织学#

20 0
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2019-12-10 yb6560

#Pathol#

30 0
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2020-01-27 维他命

#随访结果#

22 0
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2019-09-02 yangcx0915

#细胞学#

37 0
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2020-01-06 yaanren

#不典型#

26 0
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2019-06-04 一闲

#宫颈#

28 0
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2019-06-04 jktdtl

#病理学#

29 0
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2019-06-04 ms3994565386320060

#Med#

18 0

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ARCH PATHOL LAB MED：来自中国很大的经美国病理学家认证实验室的不典型鳞状细胞的宫颈细胞学报告率和组织学随访结果

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