Eur Respir J:育龄期多囊卵巢综合征患者的哮喘与肥胖的关系分析!

2017-06-21 xing.T MedSci原创

这项研究表明多囊卵巢综合征状态和超重/肥胖状态与哮喘独立相关。需要进一步的前瞻性研究来探索来支持哮喘和多囊卵巢综合征之间相关性的可能机制。

最近的研究表明多囊卵巢综合征(PCOS)妇女可能有较高的哮喘患病率。然而,目前尚无旨在探讨多囊卵巢综合征与哮喘之间关系的流行病学研究,以及体重指数(BMI)对这种相关性的影响。

近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,该项研究是一个对澳大利亚女性健康的纵向研究数据进行的横断面分析。澳大利亚女性健康的纵向研究是一个大型的,以社区为基础的,前瞻性研究旨在评估28岁-33岁妇女中多囊卵巢综合征和哮喘之间的相关性(多囊卵巢综合征n=478,以及对照者n=8134)。

多囊卵巢综合征患者的哮喘患病率为15.2%,而无多囊卵巢综合征的妇女为10.6%(P=0.004)。多囊卵巢综合征同时患哮喘的妇女与没有哮喘的妇女相比,具有BMI较高的趋势(29.9±0.9 vs. 27.7±0.4kg/m2;P=0.054)。没有多囊卵巢综合征的哮喘妇女相比于没有哮喘的妇女有较高的BMI(26.4±0.2 vs. 24.9±0.1kg/m2;P<0.001)。调整年龄、BMI和吸烟状况后,多囊卵巢综合征与哮喘发病几率增加相关(比值比为1.34,95%可信区间为1.004-1.79,P=0.047)。

这项研究表明多囊卵巢综合征状态和超重/肥胖状态与哮喘独立相关。需要进一步的前瞻性研究来探索来支持哮喘和多囊卵巢综合征之间相关性的可能机制。

原始出处:

Thaw D. Htet,et al. Asthma in reproductive-aged women with polycystic ovary syndrome and association with obesity. Eur Respir J.2007.http://erj.ersjournals.com/content/49/5/1601334

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    2017-11-14 sjq038
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    2017-06-23 zhouqu_8
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    2017-06-21 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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    2017-06-21 131****1460

    学习了受益匪浅。

    0

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    2017-06-21 1dd8aa01m06(暂无匿称)

    学习了很好的内容

    0

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    2017-06-21 胖红

    学习了很多的事情,

    0

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