JAHA: 早年经历中国大饥荒者,成年后易患心血管病!上海瑞金医院毕宇芳等发表REACTION研究

2020-04-04 朱朱 中国循环杂志

既往研究发现,早年因遭受饥荒而营养不良的人,成年后出现糖尿病和代谢综合征的风险明显增加。

既往研究发现,早年因遭受饥荒而营养不良的人,成年后出现糖尿病和代谢综合征的风险明显增加。

4月1日,上海交通大学医学院附属瑞金医院毕宇芳、陆洁莉等发表的REACTION研究提示,早年遭遇中国大饥荒而营养不良的人,成年后(40岁以后)发生心血管病的风险显著增加,早年生活在严重饥荒地区的人风险更高。

研究者指出,该研究表明,儿童期和青少年时期的营养状况对于成年后心血管病的预防有重要作用。他们认为,早年营养不良与成年后心血管病发生风险之间的关系可能在一定程度上与代谢综合征风险增加有关。

该研究于2011~2012年从全国25个中心纳入近26万名≥40岁的成年人。

结果显示,与从未经历饥荒的人相比,早年经历过饥荒的人中心血管病、心肌梗死、中风、冠心病发生风险显著增加。

多因素logistic回归分析显示,在儿童期经历过饥荒的人中,心血管病、心肌梗死、中风、冠心病发生风险分别增加35%、59%、40%、44%。

在青少年时期经历过饥荒的人中,上述事件的发生风险分别增加52%、107%、92%、83%。

该研究显示,与早年生活在饥荒相对不严重地区的人相比,早年生活在饥荒严重地区的人成年后出现心血管病的风险显著增加。

原始出处:
Rui Du,et al. Early‐Life Famine Exposure and Risk of Cardiovascular Diseases in Later Life: Findings From the REACTION Study. J Am Heart Assoc, 2020, 9: e014175

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2009632, encodeId=77d32009632d4, content=<a href='/topic/show?id=54b8440545a' target=_blank style='color:#2F92EE;'>#大饥荒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44054, encryptionId=54b8440545a, topicName=大饥荒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Oct 07 21:32:16 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793170, encodeId=91841e93170f8, content=<a href='/topic/show?id=0b6e15215b6' target=_blank style='color:#2F92EE;'>#ReACT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15215, encryptionId=0b6e15215b6, topicName=ReACT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Tue Aug 04 13:32:16 CST 2020, time=2020-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644841, encodeId=d8c0164484102, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Sun Nov 08 19:32:16 CST 2020, time=2020-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2019981, encodeId=d23c2019981d2, content=<a href='/topic/show?id=b357199535c' target=_blank style='color:#2F92EE;'>#上海瑞金医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19953, encryptionId=b357199535c, topicName=上海瑞金医院)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQHWdlyPWPmuHjfEXicudmC0dJ6SN5PHzglbDHibXpT1VXF2fKDnTzl2Eib4Pf94p58cnSKA3ZfGdFQ/132, createdBy=c44f2500101, createdName=ms2694732865965676, createdTime=Fri Nov 06 02:32:16 CST 2020, time=2020-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268246, encodeId=c4551268246de, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Apr 06 02:32:16 CST 2020, time=2020-04-06, status=1, ipAttribution=)]
    2020-10-07 drj2003
  2. [GetPortalCommentsPageByObjectIdResponse(id=2009632, encodeId=77d32009632d4, content=<a href='/topic/show?id=54b8440545a' target=_blank style='color:#2F92EE;'>#大饥荒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44054, encryptionId=54b8440545a, topicName=大饥荒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Oct 07 21:32:16 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793170, encodeId=91841e93170f8, content=<a href='/topic/show?id=0b6e15215b6' target=_blank style='color:#2F92EE;'>#ReACT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15215, encryptionId=0b6e15215b6, topicName=ReACT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Tue Aug 04 13:32:16 CST 2020, time=2020-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644841, encodeId=d8c0164484102, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Sun Nov 08 19:32:16 CST 2020, time=2020-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2019981, encodeId=d23c2019981d2, content=<a href='/topic/show?id=b357199535c' target=_blank style='color:#2F92EE;'>#上海瑞金医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19953, encryptionId=b357199535c, topicName=上海瑞金医院)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQHWdlyPWPmuHjfEXicudmC0dJ6SN5PHzglbDHibXpT1VXF2fKDnTzl2Eib4Pf94p58cnSKA3ZfGdFQ/132, createdBy=c44f2500101, createdName=ms2694732865965676, createdTime=Fri Nov 06 02:32:16 CST 2020, time=2020-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268246, encodeId=c4551268246de, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Apr 06 02:32:16 CST 2020, time=2020-04-06, status=1, ipAttribution=)]
    2020-08-04 hittouch
  3. [GetPortalCommentsPageByObjectIdResponse(id=2009632, encodeId=77d32009632d4, content=<a href='/topic/show?id=54b8440545a' target=_blank style='color:#2F92EE;'>#大饥荒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44054, encryptionId=54b8440545a, topicName=大饥荒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Oct 07 21:32:16 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793170, encodeId=91841e93170f8, content=<a href='/topic/show?id=0b6e15215b6' target=_blank style='color:#2F92EE;'>#ReACT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15215, encryptionId=0b6e15215b6, topicName=ReACT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Tue Aug 04 13:32:16 CST 2020, time=2020-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644841, encodeId=d8c0164484102, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Sun Nov 08 19:32:16 CST 2020, time=2020-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2019981, encodeId=d23c2019981d2, content=<a href='/topic/show?id=b357199535c' target=_blank style='color:#2F92EE;'>#上海瑞金医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19953, encryptionId=b357199535c, topicName=上海瑞金医院)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQHWdlyPWPmuHjfEXicudmC0dJ6SN5PHzglbDHibXpT1VXF2fKDnTzl2Eib4Pf94p58cnSKA3ZfGdFQ/132, createdBy=c44f2500101, createdName=ms2694732865965676, createdTime=Fri Nov 06 02:32:16 CST 2020, time=2020-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268246, encodeId=c4551268246de, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Apr 06 02:32:16 CST 2020, time=2020-04-06, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2009632, encodeId=77d32009632d4, content=<a href='/topic/show?id=54b8440545a' target=_blank style='color:#2F92EE;'>#大饥荒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44054, encryptionId=54b8440545a, topicName=大饥荒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Oct 07 21:32:16 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793170, encodeId=91841e93170f8, content=<a href='/topic/show?id=0b6e15215b6' target=_blank style='color:#2F92EE;'>#ReACT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15215, encryptionId=0b6e15215b6, topicName=ReACT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Tue Aug 04 13:32:16 CST 2020, time=2020-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644841, encodeId=d8c0164484102, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Sun Nov 08 19:32:16 CST 2020, time=2020-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2019981, encodeId=d23c2019981d2, content=<a href='/topic/show?id=b357199535c' target=_blank style='color:#2F92EE;'>#上海瑞金医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19953, encryptionId=b357199535c, topicName=上海瑞金医院)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQHWdlyPWPmuHjfEXicudmC0dJ6SN5PHzglbDHibXpT1VXF2fKDnTzl2Eib4Pf94p58cnSKA3ZfGdFQ/132, createdBy=c44f2500101, createdName=ms2694732865965676, createdTime=Fri Nov 06 02:32:16 CST 2020, time=2020-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268246, encodeId=c4551268246de, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Apr 06 02:32:16 CST 2020, time=2020-04-06, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2009632, encodeId=77d32009632d4, content=<a href='/topic/show?id=54b8440545a' target=_blank style='color:#2F92EE;'>#大饥荒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44054, encryptionId=54b8440545a, topicName=大饥荒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Oct 07 21:32:16 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793170, encodeId=91841e93170f8, content=<a href='/topic/show?id=0b6e15215b6' target=_blank style='color:#2F92EE;'>#ReACT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15215, encryptionId=0b6e15215b6, topicName=ReACT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Tue Aug 04 13:32:16 CST 2020, time=2020-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644841, encodeId=d8c0164484102, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Sun Nov 08 19:32:16 CST 2020, time=2020-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2019981, encodeId=d23c2019981d2, content=<a href='/topic/show?id=b357199535c' target=_blank style='color:#2F92EE;'>#上海瑞金医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19953, encryptionId=b357199535c, topicName=上海瑞金医院)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQHWdlyPWPmuHjfEXicudmC0dJ6SN5PHzglbDHibXpT1VXF2fKDnTzl2Eib4Pf94p58cnSKA3ZfGdFQ/132, createdBy=c44f2500101, createdName=ms2694732865965676, createdTime=Fri Nov 06 02:32:16 CST 2020, time=2020-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268246, encodeId=c4551268246de, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Apr 06 02:32:16 CST 2020, time=2020-04-06, status=1, ipAttribution=)]
    2020-04-06 zhaohui6731

相关资讯

JACC:心肺健康与死亡率呈负相关

三十年前,心肺健康与死亡率之间的负相关得到了有力的证明。本研究的目的是评估自那时以来在疾病预防、检测和治疗方面的重大进展是否改变了这种联系。

JACC:基于瑜伽的护理可以改善急性心梗患者预后

鉴于印度缺乏心脏康复(CR)计划,且全世界范围内的CR覆盖率都很低,因此迫切需要寻找廉价的替代性CR模型。本研究旨在通过一项多中心随机对照试验,评估以瑜伽为基础的CR(瑜珈护理)对主要心血管事件和自我

Circulation: 发表中国新冠肺炎心血管急危重症专家共识

3月28日,Circulation杂志在线发表了中国《新型冠状病毒肺炎疫情防控期间心血管急危重症患者临床处理原则的专家共识》英文版。

JACC:移动健康技术可以减少房颤患者不良预后的发生

目前对于房颤的治疗局限于对房颤(AF)的低检测率和低依从性,因此,需要加强对AF管理采取更加全面和综合的方法。本研究的目的是确定与普通的策略相比,移动健康(mHealth)技术支持的房颤综合管理策略是

JACC:美国左心耳封堵注册数据库的近3年病例总结研究

左心耳封堵(LAAO)预防心房颤动患者卒中的2项随机临床试验已经进行了评价,但是批准后的临床数据有限。本研究的目的是描述美国国家心血管数据注册中心(NCDR)LAAO注册中心(LAAO注册数据库)在其

American Heart Association:极端高温天气会增加1~2倍心血管死亡!

当新冠病毒疫情在中国暴发时,中国之外似乎尚不觉危险已经临近;当气候变暖时,灾难难道仅仅会落在极地动物身上?