JACC:心肺健康与死亡率呈负相关

2020-04-02 MedSci原创 MedSci原创

三十年前,心肺健康与死亡率之间的负相关得到了有力的证明。本研究的目的是评估自那时以来在疾病预防、检测和治疗方面的重大进展是否改变了这种联系。

三十年前,心肺健康与死亡率之间的负相关得到了有力的证明。本研究的目的是评估自那时以来在疾病预防、检测和治疗方面的重大进展是否改变了这种联系。

共有47862名男性完成了基线检查,包括最大耐量跑步机测试,队列1(n=24475)于1971年至1991年进行检查,并随访死亡率至1992年,队列2(n=23387)于1992年至2013年进行检查,并随访死亡率至2014年。分析结果显示,心肺健康与死亡率和心血管疾病死亡率呈明显的相反趋势(p<0.001)。心肺健康程度和癌症死亡率之间的趋势在队列1中是明显的,而在队列2中不明显。队列1和队列2参与者每增加1-MET的心肺健康,全因死亡率的HR分别为0.86 (95% cl: 0.82-0.90) 和0.87 (95% cl: 0.83-0.91)。

研究结果显示,尽管自心肺健康首次被证明与死亡率相关以来,疾病预防、检测和治疗方面取得了重大进展,但心肺健康与死亡率之间的反比关系在当代男性队列中仍然是一致的。

原始出处:

Stephen W et al.Relevance of Fitness to Mortality Risk in Men Receiving Contemporary Medical Care.JACC.2020 Apr.

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    2021-01-06 hbwxf
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    2020-07-03 aids222
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    2020-04-04 hmwwww

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