Heart:先天性心脏病患者妊娠应该怎么办?

2017-07-30 MedSci MedSci原创

目前,手术条件的改善使得更多患有先天性心脏病(CHD)的女性重获新生。那么,那些CHD的妇女希望妊娠时应该怎么做呢?首先,希望开始怀孕的CHD女性需要进行妊娠前咨询。这个咨询应该涵盖几个问题,如母亲的长期预后,生育率和流产率,婴儿CHD的复发风险,怀孕期间的药物治疗,孕产妇风险和结局估计,胎儿预期结果和怀孕计划。其次,使用产前诊断或产前诊断绒毛膜(绒毛取样)或羊膜穿刺,患有遗传缺陷的患者还可以进行

目前,手术条件的改善使得更多患有先天性心脏病(CHD)的女性重获新生。


那么,那些CHD的妇女希望妊娠时应该怎么做呢?

首先,希望开始怀孕的CHD女性需要进行妊娠前咨询。这个咨询应该涵盖几个问题,如母亲的长期预后,生育率和流产率,婴儿CHD的复发风险,怀孕期间的药物治疗,孕产妇风险和结局估计,胎儿预期结果和怀孕计划。

其次,使用产前诊断或产前诊断绒毛膜(绒毛取样)或羊膜穿刺,患有遗传缺陷的患者还可以进行产前基因检测。高危患者需要集中治疗。

最后,至关重要的是,应为所有心脏病患者提供专门的转移计划。低收入国家和中等收入国家的产妇死亡率高于高收入国家14倍,她们更需要额外的专业的照料。

原始出处:
Roos-Hesselink JW, Budts W, et al. Organisation of care for pregnancy in patients with congenital heart disease. Heart. 2017 Jul 24. pii: heartjnl-2017-311758. doi: 10.1136/heartjnl-2017-311758. 

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    2017-08-05 周周人

    学习。

    0

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    2017-08-01 zhaojie88
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    2017-08-01 huirong
  4. 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createdName=zhaojie88, createdTime=Tue Aug 01 03:56:00 CST 2017, time=2017-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369305, encodeId=4bf0136930550, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Aug 01 03:56:00 CST 2017, time=2017-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562644, encodeId=14381562644f7, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Aug 01 03:56:00 CST 2017, time=2017-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228459, encodeId=40bc2284599b, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Jul 31 12:49:42 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228431, encodeId=2fa12284317d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Mon Jul 31 10:09:30 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228314, encodeId=a2122283148c, content=学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jul 31 07:18:28 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228297, encodeId=d90222829eca, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Mon Jul 31 06:25:15 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228288, encodeId=d9cd22828806, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Mon Jul 31 06:15:04 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228247, encodeId=c9b222824e3c, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Mon Jul 31 01:37:59 CST 2017, time=2017-07-31, status=1, ipAttribution=)]
    2017-08-01 slcumt
  5. 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likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Mon Jul 31 01:37:59 CST 2017, time=2017-07-31, status=1, ipAttribution=)]
    2017-07-31 清风拂面

    谢谢分享,学习了

    0

  6. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Mon Jul 31 10:09:30 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228314, encodeId=a2122283148c, content=学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jul 31 07:18:28 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228297, encodeId=d90222829eca, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Mon Jul 31 06:25:15 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228288, encodeId=d9cd22828806, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Mon Jul 31 06:15:04 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228247, encodeId=c9b222824e3c, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Mon Jul 31 01:37:59 CST 2017, time=2017-07-31, status=1, ipAttribution=)]
    2017-07-31 往日如昨

    学习了谢谢分享

    0

  7. 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likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Mon Jul 31 01:37:59 CST 2017, time=2017-07-31, status=1, ipAttribution=)]
    2017-07-31 flysky120

    学习一下知识

    0

  8. 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likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Mon Jul 31 01:37:59 CST 2017, time=2017-07-31, status=1, ipAttribution=)]
    2017-07-31 laoli

    学习了,谢谢分享!

    0

  9. 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    2017-07-31 189****7206

    学习了受益匪浅

    0

  10. 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likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Mon Jul 31 01:37:59 CST 2017, time=2017-07-31, status=1, ipAttribution=)]
    2017-07-31 jacob9231

    学习了谢谢分享

    0

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肥胖或体重过轻都会增加心脏外科手术不良后果的风险,体重系数能否成为围术期不良后果的一项可改变的危险因素,还有待未来进一步研究发现。

盘点:先天性心脏病近期重要研究进展一览

先天性心脏病是先天性畸形中最常见的一类,约占各种先天畸形的28%,先天性心脏病发病率不容小视,约占出生活婴的0.4%~1%。先天性心脏病的种类很多,其临床表现主要取决于畸形的大小和复杂程度。复杂而严重的畸形在出生后不久即可出现严重症状,甚至危及生命。这里梅斯小编整理了近期关于先天性心脏病的研究进展与大家分享。【1】Circulation:叶酸水平与先天性心脏病的相关性近期,为了检查汉族人群中叶

Circulation:左心发育不良综合征2期姑息治疗的更佳时机

在几乎没有危险因素的婴儿中,Norwood手术后3-6个月内进展到S2P与最大TFS相关。

JACC:先天性心脏病患者的蛋白丢失肠病病因研究

蛋白丢失肠病(PLE),其特点是在肠内失去蛋白质,是先天性心脏病患者的一种毁灭性的并发症。PLE的病因尚不清楚,但怀疑与淋巴管有关。

Circulation:胎儿先天性心脏病与妊娠期高血压风险的关联

一些先天性心脏病和先兆子痫可能涉及了某些共同的病理生理机制。不同孕次间的强相关性支持这种关联是以母亲为主导的。

Heart:先天性心脏病儿童的冠状动脉解剖学异常!

在二叶瓣型主动脉瓣(BAV)患者中,冠状动脉解剖是变化的。此前,已经有研究描述了相关冠状动脉,但是数据很少,特别是当与复杂的先天性心脏病(CHD)相关时,相关资料更是少之又少。近期,一项发表在杂志Heart上的研究旨在描述这些患者的冠状动脉模式。此项研究在84例伴有BAV及相关CHD患者的死后心脏标本中,对冠状动脉口的位置和高度进行了研究,并分析了与BAV形态的关联。此项研究结果显示:在23%和3