EASD 2016:震惊!多不饱和脂肪酸摄入过多,竟然会增加2型糖尿病风险!

2016-09-16 Mechront 译 MedSci原创

第52届欧洲糖尿病学会年会(EASD 2016)称:与每日摄入少于1.3克ω-3和ω-6多不饱和脂肪酸的女性相比较,摄入更高含量的这些物质,更有可能发展为2型糖尿病。 来自法国INSERM流行病学和人口健康研究中心的流行病学家Courtney Dow和同事们一起,对71334名40到65岁法国女性进行了研究(来自E3N队列),从1990年开始前瞻性研究,调查与癌症和其他非传染性疾病相关的危险

第52届欧洲糖尿病学会年会(EASD 2016)称:与每日摄入少于1.3克ω-3和ω-6多不饱和脂肪酸的女性相比较,摄入更高含量的这些物质,更有可能发展为2型糖尿病

来自法国INSERM流行病学和人口健康研究中心的流行病学家Courtney Dow和同事们一起,对71334名40到65岁法国女性进行了研究(来自E3N队列),从1990年开始前瞻性研究,调查与癌症和其他非传染性疾病相关的危险因素。每2-3年,参与者完成一份自填式问卷,1993年完成了一份经验证的食物频率问卷。

研究人员发现,摄入ω-3多不饱和脂肪酸的量与2型糖尿病风险之间具有一定联系:摄入量>1.6克 vs 摄入量<1.3克,2型糖尿病风险增加26%。

根据体重对参与者进行分层,研究人员发现,对于正常体重(BMI<25)女性,总的多不饱和脂肪酸的摄入量与2型糖尿病风险有关;每天摄入量≥15.3克 vs ≤12克,2型糖尿病风险增加22%。不管是超重还是正常体重女性,摄入高水平的ω-3脂肪酸,都会增加2型糖尿病风险。

细分ω-3多不饱和脂肪酸,食物中二十二碳五烯酸(DPA;每天0.08克)摄入量的增加,女性2型糖尿病风险增加(超重:增加45%;正常体重:增加54%)。超重女性α-亚麻酸(ALA)摄入量≥1.14克 vs <0.9克,2型糖尿病风险增加17%。

细分ω-6多不饱和脂肪酸,只有花生四烯酸与糖尿病有关。正常体重女性每日摄入量≥0.25克 vs <0.19克,2型糖尿病风险增加50%;同等比较条件下,超重女性的2型糖尿病风险增加74%。

校正肉类摄入后,DPA和花生四烯酸摄入量与2型糖尿病风险之间的联系仍存在。研究人员报告说,队列参与者的DPA主要来源是肉类(31.3%)和鱼/海鲜(22.6%);花生四烯酸的主要来源是肉类(42.7%)、鱼/海鲜(10.7%)和鸡蛋(9.7%)。

原始出处:

Dow C, et al. Poster #286. Presented at: 52nd EASD Annual Meeting; Sept. 12-16, 2016; Munich.

Fatty acid consumption linked to type 2 diabetes risk in women.Healio.September 15, 2016

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    2016-12-31 okhuali
  4. 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    2016-09-22 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  6. 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  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378705, encodeId=d17e13e8705f4, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Sat Sep 17 23:24:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129698, encodeId=5514129698bf, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Sep 17 18:58:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129081, encodeId=23ea1290814a, content=很好的内容,继续学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ceb079804, createdName=lhl629, createdTime=Sat Sep 17 07:16:00 CST 2016, time=2016-09-17, status=1, ipAttribution=)]
    2016-09-17 qilu_qi
  8. 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  9. [GetPortalCommentsPageByObjectIdResponse(id=1932117, encodeId=3ccd193211e5a, content=<a href='/topic/show?id=286810126909' target=_blank style='color:#2F92EE;'>#饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101269, encryptionId=286810126909, topicName=饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b96f328, createdName=wwzzly, createdTime=Wed Apr 26 17:24:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689345, encodeId=a0ee16893452d, content=<a href='/topic/show?id=a8f3205636d' target=_blank style='color:#2F92EE;'>#不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20563, encryptionId=a8f3205636d, topicName=不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=null, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378705, encodeId=d17e13e8705f4, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Sat Sep 17 23:24:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129698, encodeId=5514129698bf, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Sep 17 18:58:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), 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    2016-09-17 忠诚向上

    好好学习一下

    0

  10. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378705, encodeId=d17e13e8705f4, content=<a href='/topic/show?id=d27b430265e' target=_blank style='color:#2F92EE;'>#多不饱和脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43026, encryptionId=d27b430265e, topicName=多不饱和脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=284b425, createdName=zll0625, createdTime=Sat Sep 17 23:24:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129698, encodeId=5514129698bf, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Sep 17 18:58:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129081, encodeId=23ea1290814a, content=很好的内容,继续学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ceb079804, createdName=lhl629, createdTime=Sat Sep 17 07:16:00 CST 2016, time=2016-09-17, status=1, ipAttribution=)]
    2016-09-17 lhl629

    很好的内容,继续学习。

    0

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BMJ:植物性脂肪增加冠状动脉疾病患者死亡风险

美国国立卫生研究所的Ramsden等的研究表明,富含多不饱和脂肪酸的亚油酸干预性饮食增加冠状动脉疾病患者全因死亡率。研究论文2月5日发表于《英国医学杂志》(BMJ 2013,346:e8707)。 Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evalu

PLoS Med:多不饱和脂肪酸与2型糖尿病(EPIC-InterAct研究)

目的:探究n-3和n-6多不饱和脂肪酸(PUFA)与2型糖尿病(T2D)的关系。方法:使用气相色谱分析对12132名T2D和15919名对照组(来自在8个欧洲国家进行的欧洲癌症和营养的前瞻性调查(EPIC)相互作用研究(EPIC-InterAct))进行血浆磷脂PUFAs分析。对总的和国家特异性联系均进行了分析;此外还系统地回顾了已发表的有关PUFAs和T2D联系的前瞻性研究。结果:EPIC-In