硫酸镁的8种临床用法

2015-12-02 佚名 医学之声

①镇惊厥  10%硫酸镁10毫升深部肌肉注射或用 5%葡萄糖稀释成2%~2.5%的溶液缓慢滴注。   此时硫酸镁可抑制中枢神经系统,松弛骨骼肌,具有镇静、抗痉挛以及减低颅内压等作用。常用于治疗惊厥、子痫、尿毒症、破伤风及高血压脑病等。   但应注意直接静脉注射或大剂量肌肉注射硫酸镁很危险,一般25%硫酸镁每次最多用15毫升即可。使用时应注意观察病人呼

①镇惊厥 

10%硫酸镁10毫升深部肌肉注射或用 5%葡萄糖稀释成2%~2.5%的溶液缓慢滴注。
 
此时硫酸镁可抑制中枢神经系统,松弛骨骼肌,具有镇静、抗痉挛以及减低颅内压等作用。常用于治疗惊厥、子痫、尿毒症、破伤风及高血压脑病等。
 
但应注意直接静脉注射或大剂量肌肉注射硫酸镁很危险,一般25%硫酸镁每次最多用15毫升即可。使用时应注意观察病人呼吸和血压情况,膝反射迟钝是镁离子足量的重要标志。
 
②通大便

口服硫酸镁在肠道吸收很少,口服硫酸镁有良好的导泻功能,因此硫酸镁又叫泻盐。
 
口服硫酸镁水溶液到达肠腔后,具有一定渗透压,使肠内水分不被肠壁吸收。
 
肠内保有大量水分,能机械地刺激肠的蠕动而排便。因此硫酸镁可用于治疗便秘、肠内异常发酵;与驱虫剂并用,可使肠虫易于排出。可每次将5 ~20克硫酸镁溶于100~400毫升温开水中,清晨一次口服。
 
③排结石

硫酸镁能刺激十二指肠粘膜,反射性地引起总胆管括约肌松弛、胆囊收缩,从而促进胆囊排空,有利胆之功效。可用于治疗胆囊炎胆石症,每次 2~5克,每日3次,饭前或餐间口服。
 
④降血压

对心血管系统的作用,注射给药,过量镁离子可直接扩张周围血管平滑肌,引起交感神经节传递障碍,从而血管扩张,血压下降。
 
肌内注射一次1g,10%溶液,每次10 毫升;
 
静脉滴注,一次1-2.5g,将25%溶液 10毫升用5%葡萄糖稀释成1%浓度缓慢注射。
 
⑤救哮喘

硫酸镁通过抑制细胞对钙的摄取而使支气管平滑肌松弛,有助于危重哮喘时症状的缓解。
 
药物剂量:25~40mg/(kg·d)(最大 2g/d),分1~2次,加入10%葡萄糖溶液20ml缓慢静脉滴注(20分钟以上),酌情使用1~3天。
 
⑥治早产

镁离子能直接抑制子宫平滑肌,可治疗早产。硫酸镁静脉注射与滴注,首次4克,用25%葡萄糖20毫升溶解5分钟内缓慢注射,以后用25%硫酸镁60 毫升,加于5%葡萄糖1000毫升静脉滴注,每小时2克,直到宫缩停止后2 小时。
 
但是,连续用药不能过长,有研究表明「暴露于镁超过1星期的新生儿与暴露于镁仅3天的新生儿相比,能够观察到其有显明更多的骨异常」可能是由于胎儿血镁过多和由此产生的低血钙症所致。
 
⑦低镁症

镁具有许多与钾相类似的生理功能。由于镁缺乏的临床表现与缺钾相似,故缺镁往往易被忽视。在缺钾时经过补钾而症状仍无改善时,应首先考虑到缺镁的可能,这样才可使低镁血症得到及时纠正。因此,长期输液的病人,在补钾的同时要注意补镁。每日输液中加1克硫酸镁,可防止低镁血症的发生。
 
⑧消炎去肿

硫酸镁有消炎去肿的功效,所以50% 硫酸镁溶液热敷患处可以消肿。
 
注意:

血镁过量可引起呼吸抑制、血压骤降、心跳骤停而致死。肌腱反射消失是呼吸抑制的先兆,因此,在连续用药期间应经常检查腱反射。出现中毒时应立即进行人工呼吸,并缓慢静脉注射氯化钙或葡萄糖酸钙紧急抢救。透析疗法可迅速清除体内镁离子,加速镁离子排泄。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (9)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-04 老段

    内服外用?

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-03 lixh1719

    我觉得镁剂有待深入研究

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-03 cmn

    收藏

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-03 lpapple

    物美价廉的好药

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-02 午夜星河

    有道理

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=49155, encodeId=39844915524, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49156, encodeId=30bb49156f8, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:11:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44692, encodeId=a9d244692c6, content=内服外用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Fri Dec 04 06:52:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1445725, encodeId=089d1445e257e, content=<a href='/topic/show?id=6634e3575cf' target=_blank style='color:#2F92EE;'>#硫酸镁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73575, encryptionId=6634e3575cf, topicName=硫酸镁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0f15173844, createdName=xxxx1051, createdTime=Fri Dec 04 05:57:00 CST 2015, time=2015-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44523, encodeId=54804452340, content=我觉得镁剂有待深入研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Thu Dec 03 11:28:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44501, encodeId=ca82445019b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 03 09:42:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44487, encodeId=e76b4448ed6, content=物美价廉的好药, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d9077449, createdName=lpapple, createdTime=Thu Dec 03 06:50:00 CST 2015, time=2015-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44476, encodeId=3b29444e63e, content=有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Dec 02 22:19:00 CST 2015, time=2015-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44416, encodeId=031e4441620, content=药理学过, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=974f1667182, createdName=杨晨舟, createdTime=Wed Dec 02 15:46:00 CST 2015, time=2015-12-02, status=1, ipAttribution=)]
    2015-12-02 杨晨舟

    药理学过

    0

相关资讯

FDA限制使用硫酸镁用于预防早产

5月30日,美国食品药品管理局(FDA)建议临床医生,在预防早产时不要对孕妇连续使用硫酸镁超过5至7天,因为这种药物可能会对正在发育的胎儿骨骼有损害。FDA解释说,硫酸镁只被批准用于预防子痫前期的癫痫发作,其用于安胎的超出适应症范围的标签外使用能导致婴儿低钙水平、骨量减少或者骨折。 针对这种药物影响的警示内容已被列入药物标签中,其致畸类别也正由A类改为D类。同时药品标签也被修订,强调注射用硫酸镁

FDA修改硫酸镁注射液药品标签

  美国食品与药物管理局(FDA)基于“若妊娠女性使用硫酸镁注射液超过5~7天,可能导致发育中胎儿出现低血钙和骨骼问题(包括骨质疏松和骨折)”这一新安全信息,修改硫酸镁注射液药品标签。   硫酸镁注射液被用于预防先兆子痫妊娠女性出现癫痫发作,并治疗子痫妊娠女性的癫痫发作。使用该药物治疗早产是标签外用药。   硫酸镁注射液药品标签新增加内容包括:   ⑴ 妊娠期连续应用该药物治疗早产

Lancet RM:硫酸镁对急性重症哮喘患儿有效(MAGNETIC研究)

几乎没有证据表明雾化吸入型硫酸镁(MgSO4)在儿童急性哮喘中的作用,英国学者的一项研究评估了儿童急性重症哮喘使用硫酸镁治疗的效果。结果显示,总体来说,作为标准治疗的辅助治疗,雾化吸入型等渗硫酸镁在急性重症哮喘患儿的平均ASS评分中没有展示出显著的临床改善。但是,在严重发作(血氧饱和度小于92%)和进行性症状持续小于6小时的患儿中可观察到最大的临床反应。相关研究发表于《柳叶刀》杂志(the Lan

FDA警告:慎用硫酸镁阻止早产

  2013年5月30日,美国食品药品管理局(FDA)发布了一则警告,反对硫酸镁注射剂用于阻止孕妇早产的用药时间>5~7天,以免导致胎儿风险。胎儿可能出现低钙水平、骨质减少以及骨折,可导致损害的最短治疗时间尚不清楚。   硫酸镁已被批准用于预防先兆子痫患者癫痫以及控制子痫患者癫痫发作,而用于阻止早产则属于超适应证使用。   FDA已通过其不良事件报告系统确认了18例有关宫内硫酸镁暴露新生儿骨骼

NEJM:院前对脑卒中患者用硫酸镁保护脑神经

院前对脑卒中患者用硫酸镁保护脑神经 背景 硫酸镁应用于处于脑卒中发作潜伏期的患者身上已被证明是有保护神经的作用,并且若是在脑卒中表现初期使用则可以体现出硫酸镁潜在的功效和可被接受的安全性能。但是推迟启动脑神经保护药物的研发这一态度和观点已经阻碍了脑神经保护药物研发早期的三期临床试验的进展。方式 我们随机分配怀疑发生中风的病人为两组,让他们在脑卒中症状出现的2个小时内分别接受静脉注射硫酸镁或者