Br J Anaesth:术前急性吸烟不会增加术间误吸的风险

2015-10-06 张森 译 MedSci原创

近日,来自法国里昂大学的Lazaar教授等人进行了一项前瞻性、随机、单盲、交叉研究,旨在评估急性吸烟对经常吸烟的人群胃内容物的影响。该研究已发表于Br J Anaesth。   本次研究招募了经常吸烟的志愿者,并将这些志愿者随机分为两组:对照组,吸烟组。研究人员首先使用超声对志愿者的胃窦面积进行检测,然后对照组志愿者进行30min的等待期,吸烟组志愿者吸烟2支。并在初次超声检

近日,来自法国里昂大学的Lazaar教授等人进行了一项前瞻性、随机、单盲、交叉研究,旨在评估急性吸烟对经常吸烟人群的胃内容物的影响。该研究已发表于Br J Anaesth。

本次研究招募了经常吸烟的志愿者,并将这些志愿者随机分为两组:对照组和吸烟组。研究人员首先使用超声对志愿者的胃窦面积进行检测,然后对照组志愿者进行30min的等待期,吸烟组志愿者吸烟2支。并在初次超声检测后的306090120min分别使用超声对所有志愿者的胃窦面积进行检测,计算0-30min0-60min0-90min0-120min期间两组志愿者胃窦面积的变异率。本次研究的主要终点为急性吸烟后120min内志愿者胃窦面积的变异率。

结果显示,在0-120min期间两组志愿者胃窦面积的变化相当;而在吸烟组志愿者中,由于胃窦面积没有显著的减少,两组志愿者在0-30min、0-60min、0-90min期间胃窦面积的变化则不具等效性。


最后研究者得出结论:研究过程中,经常吸烟志愿者在术前急性吸烟并没有对其胃内容物的变化产生影响,同时该研究结果也支持急性术前吸烟不可能改变健康经常吸烟人群胃内容物误吸的风险这一临床建议。

原始出处:

Lazaar S,Boselli E,et al.Effect of acute cigarette smoking on gastric contents in regular smoker volunteers. A prospective randomizedcross-over study.Br J Anaesth.2015 Oct;115(4):590-4.

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    2016-09-15 1e10c84am36(暂无匿称)

    文章不错,值得拜读

    0

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    2016-04-11 Wechat4343a314

    前瞻性研究的结论,可关注。

    0

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    2016-04-22 AspirantSuo
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    2015-12-26 hixiaoluo

    受教

    0