Hypertension:动脉硬化跟心衰到底啥关系?

2016-12-27 xing.T MedSci原创

通过cf-PWV来测量的动脉硬化,在对传统的心血管危险因素进行调整后,与心衰或其亚型的风险并不是独立相关的。

动脉硬化程度越高与动脉粥样硬化事件风险增加相关。然而,独立于其他危险因素,其对心力衰竭及其亚型(射血分数保留的心衰和射血分数减少的心衰)风险的影响尚未有研究报道。近日,心血管权威杂志Hypertension上发表一篇研究文章,旨在明确这一问题。

在这项研究中,研究者纳入了健康ABC(健康、衰老和身体成分)研究中的没有发生心衰但在研究之初通过颈动脉股动脉脉搏波传导速度(cf-PWV)测量伴有动脉硬化的参与者(n=2290)。研究人员构建了调整后的Cox比例风险模型来确定的连续的和数据源分类的cf-PWV测量(三分位数)和心衰及其亚型(射血分数保留的心衰 [射血分数>45%]和射血分数减少的心衰[射血分数≤45%])发生率之间的相关性。

经过11.4年的随访,研究者观察到了390次心衰事件(162次为射血分数保留的心衰和145次射血分数减少的心衰事件)。在调整后的分析中,研究者发现调整年龄、性别、种族、平均动脉压和心率后,较高的cf-PWV与更高的心衰风险相关(位于cf-PWV第三组三分位数范围的参与者比上第一组三分位数范围的参与者的风险比[95%的置信区间]为1.35 [1.05-1.73])。


然而,该相关性在额外对其他心血管危险因素进行调整后变得不显著(风险比[95%可信区间]为1.14 [0.88-1.47])。调整潜在的混杂因素后,cf-PWV速度也与射血分数保留的心衰和射血分数减少的心衰的风险不相关(位于cf-PWV第三组三分位数范围的参与者比上第一组三分位数范围的参与者大部分调整后的风险比对于射血分数保留的心衰为1.06 [0.72-1.56];对于射血分数减少的心衰为1.28 [0.83-1.97])。

总之,通过cf-PWV来测量的动脉硬化,在对传统的心血管危险因素进行调整后,与心衰或其亚型的风险并不是独立相关的。

原始出处:

Ambarish Pandey,et al. Arterial Stiffness and Risk of Overall Heart Failure, Heart Failure With Preserved Ejection Fraction, and Heart Failure With Reduced Ejection Fraction. Hypertension. December 19, 2016. 

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2038569, encodeId=023f203856954, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Sep 23 09:50:00 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726256, encodeId=c6f01e262567b, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Feb 22 21:50:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501103, encodeId=1d7a150110345, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Thu Dec 29 13:50:00 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166547, encodeId=5bbb16654e64, content=文章不错,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 29 09:59:35 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166388, encodeId=27d61663889d, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85621649328, createdName=1ddc3547m22(暂无匿称), createdTime=Wed Dec 28 20:47:32 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166207, encodeId=9c7f16620ea9, content=明白了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Dec 28 06:15:44 CST 2016, time=2016-12-28, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2038569, encodeId=023f203856954, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Sep 23 09:50:00 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726256, encodeId=c6f01e262567b, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Feb 22 21:50:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501103, encodeId=1d7a150110345, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Thu Dec 29 13:50:00 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166547, encodeId=5bbb16654e64, content=文章不错,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 29 09:59:35 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166388, encodeId=27d61663889d, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85621649328, createdName=1ddc3547m22(暂无匿称), createdTime=Wed Dec 28 20:47:32 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166207, encodeId=9c7f16620ea9, content=明白了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Dec 28 06:15:44 CST 2016, time=2016-12-28, status=1, ipAttribution=)]
    2017-02-22 feather89
  3. [GetPortalCommentsPageByObjectIdResponse(id=2038569, encodeId=023f203856954, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Sep 23 09:50:00 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726256, encodeId=c6f01e262567b, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Feb 22 21:50:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501103, encodeId=1d7a150110345, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Thu Dec 29 13:50:00 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166547, encodeId=5bbb16654e64, content=文章不错,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 29 09:59:35 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166388, encodeId=27d61663889d, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85621649328, createdName=1ddc3547m22(暂无匿称), createdTime=Wed Dec 28 20:47:32 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166207, encodeId=9c7f16620ea9, content=明白了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Dec 28 06:15:44 CST 2016, time=2016-12-28, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2038569, encodeId=023f203856954, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Sep 23 09:50:00 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726256, encodeId=c6f01e262567b, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Feb 22 21:50:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501103, encodeId=1d7a150110345, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Thu Dec 29 13:50:00 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166547, encodeId=5bbb16654e64, content=文章不错,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 29 09:59:35 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166388, encodeId=27d61663889d, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85621649328, createdName=1ddc3547m22(暂无匿称), createdTime=Wed Dec 28 20:47:32 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166207, encodeId=9c7f16620ea9, content=明白了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Dec 28 06:15:44 CST 2016, time=2016-12-28, status=1, ipAttribution=)]
    2016-12-29 1e10c84am36(暂无匿称)

    文章不错,值得学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2038569, encodeId=023f203856954, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Sep 23 09:50:00 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726256, encodeId=c6f01e262567b, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Feb 22 21:50:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501103, encodeId=1d7a150110345, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Thu Dec 29 13:50:00 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166547, encodeId=5bbb16654e64, content=文章不错,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 29 09:59:35 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166388, encodeId=27d61663889d, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85621649328, createdName=1ddc3547m22(暂无匿称), createdTime=Wed Dec 28 20:47:32 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166207, encodeId=9c7f16620ea9, content=明白了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Dec 28 06:15:44 CST 2016, time=2016-12-28, status=1, ipAttribution=)]
    2016-12-28 1ddc3547m22(暂无匿称)

    有用

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2038569, encodeId=023f203856954, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Sep 23 09:50:00 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726256, encodeId=c6f01e262567b, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Feb 22 21:50:00 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501103, encodeId=1d7a150110345, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Thu Dec 29 13:50:00 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166547, encodeId=5bbb16654e64, content=文章不错,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Dec 29 09:59:35 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166388, encodeId=27d61663889d, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85621649328, createdName=1ddc3547m22(暂无匿称), createdTime=Wed Dec 28 20:47:32 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166207, encodeId=9c7f16620ea9, content=明白了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Wed Dec 28 06:15:44 CST 2016, time=2016-12-28, status=1, ipAttribution=)]
    2016-12-28 刘煜

    明白了,谢谢。

    0

相关资讯

中国微循环学会周围血管疾病专业委员会中青年委员会在哈举行腔内标准化治疗培训班

伴随社会老龄化,国人生活模式的改变,周围血管疾病发病率逐年提高。包括主动脉、颈动脉、下肢动脉和内脏动脉在内的外周动脉硬化性疾病已逐渐成为临床常见的疾病,成为危害人类健康主要问题之一。作为外周动脉硬化疾病重要治疗手段的腔内治疗得到了普及,但仍有相当一部分基层医院未能完整掌握腔内治疗的基本概念,操作也存在一些规范的地方,成为制约我国动脉硬化疾病治疗水平的一个瓶颈。为此,2016年3月26日,中国微循环

J Intern Med:减少心血管事件,金黄色葡萄球菌是如何做到的?

金黄色葡萄球菌细胞壁成分能够诱导免疫细胞产生IL-10,这种细胞因子具有抗动脉粥样硬化作用。因此,在本研究中,我们调查了热灭活金黄色葡萄球菌(HK-SA)能否抑制动脉粥样硬化的发展。 研究纳入了易患动脉粥样硬化的低密度脂蛋白 受体缺乏的小鼠,每周腹腔注射HK-SA两次,喂食西方饮食六周。 结果显示,HK-SA导致腹膜巨噬细胞和脾细胞的IL-10的产量增加1.6倍,血清IL-10的产量增

ACS Nano:神奇研究用“磁铁”指引纳米颗粒 对抗动脉硬化!

在工业化程度较高的一些国家,患动脉硬化的人特别多,动脉硬化会带来致命后果:动脉血管中出现的斑块沉积会导致中风和心脏病的发生。来自德国波恩大学的研究人员开发了一种新方法利用纳米颗粒引导新细胞靶向血管病变部位,从而对抗动脉硬化。科学家们证明在小鼠体内这些新细胞确实能够在病变部位发挥治疗效果,但在应用于人类疾病治疗之前仍然需要更多研究进行验证。   相关研究结果发表在国际学术期刊ACS N

Am J Clin Nutr:虾青素能否改善肾移植接受者动脉硬化风险?

先前有证据表明,肾移植接受者动脉粥样硬化会加速,而动脉粥样硬化会显著增加心血管疾病的发病率和死亡率。高发病率的动脉粥样硬化与动脉硬度增加、血管功能障碍、氧化应激加剧、与免疫抑制治疗相关炎症等有关。而类胡萝卜素虾青素具有强大的抗氧化和抗炎特性。因此研究者对肾移植接受者进行了一项研究,探究口服虾青素对动脉硬化、氧化应激和炎症的影响。该随机、安慰剂对照、双盲试验纳入了61名肾移植接受者,试验组每天口服虾

★做在青医:”范隆华动脉硬化工作室“暨青浦区专家(名师)工作室正式授牌

今天下午,在区人社局三楼会议室举行了青浦区专家(名师)工作室授牌仪式暨工作室主持人座谈会。我院范隆华主任医师主持的“血管科功能性动脉硬化组学研究和临床应用工作室“正式予以授牌。范隆华主任医师主持的动脉硬化工作室,以功能性动脉硬化生物标记物的组学研究为纽带,召集肾内科、神经内科、内分泌科和基础医学的专家,带领年轻的学术骨干,开展以防治动脉硬化、提高脏器功能,进而提高患者生活质量为目标的研究,具有产学