J Neurol Neurosurg Psychiatry:阿尔兹海默症患者的任务需求决定了其认知储备

2017-06-20 xuyihan MedSci原创

认知储备(CR)是维持阿尔兹海默症(AD)患者认知功能的一个重要因素,影响患者认知储备的因素可能跟阿尔兹海默症患者所需要的任务需求和语意要求有关。

认知储备(CR)是维持阿尔兹海默症(AD)患者认知功能的一个重要因素,影响患者认知储备的因素可能跟阿尔兹海默症患者所需要的任务需求和语意要求有关。

本项试验从阿尔兹海默症患者数据库中选择470例患者(138例是AD患者,332例轻度认知障碍患者)。采用线性回归模型确定教育年限对于样本人群基线和区域性皮层萎缩后认知的变化。首先,研究人员采用低(听觉语言学习辨别能力),中(听觉语言学习回忆能力),高(逻辑思考回忆能力)作为语言三个不同的需求,以低(向前数数),高(向后数数)作为不同的任务需求来测试患者的认知水平。

试验结果显示:认知储备高的患者逻辑思考延迟回忆能力是强的,同时听觉语言学习延迟回忆能力也是比较好的,向后数数的表现也符合高认知水平的情况。这项试验说明当给予阿尔兹海默症患者高要求的任务需要时患者的认知水平能维持在一个很高的水平。

原始出处:

                  
R Ryan Darby.et al.Effects of cognitive reserve depend on executive and semantic demands of the task.J Neurol Neurosurg Psychiatry.2017.

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    2018-05-22 yinhl1978
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    2017-06-22 lsndxfj
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    2017-06-20 xuyihan

    学习了 不错不错

    0

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