Hypertension:肥胖与高血压到底啥关系?

2017-02-22 xing.T MedSci原创

在墨西哥成年人中,往往超重或肥胖,一般肥胖指标比中心肥胖测量指标作为血压更强的独立预测因素,并不受阈值的影响。

一般与中心肥胖标记对血压的重要性在以前的研究中得出了不同的结论,提示可能需要人群特定的肥胖阈值。近日,心血管权威杂志Hypertension上发表一篇研究文章,研究人员对招募入墨西哥城前瞻性研究中的111911名男性和女性评估了肥胖与血压之间的相关性。

这些参与者年龄在35-89岁,无慢性疾病,且均未服用抗高血压药物。线性回归被用来估计2个一般肥胖标记(体重指数和身高调整的体重)和4个中心肥胖标记(腰围、臀围、腰臀比、腰:身高比例)对收缩压和舒张压的影响,调整相关的混杂因素。

平均(SD)肥胖水平:体重指数(28.7±4.5kg/m2)、身高调整的体重(70.2±11.2kg)、腰围(93.3±10.6cm)、臀围(104±9cm)、腰臀比(0.90±0.06)以及腰高比(0.60±0.07)。血压与无阈值肥胖水平成线性相关,在该水平以下较低的一般或中心肥胖指标与较低的血压无关。平均来说,测量的肥胖指标每增加1SD收缩压增加3mmHg,舒张压升高2mmHg(SEs<0.1mmHg),但对于腰臀比,相关性的强度约只有一半。一般肥胖指标相关性独立于中心肥胖指标,但将一般肥胖指标调整后,中心肥胖指标的相关性程度大幅减弱。在男性和女性的研究结果是相似的。

在墨西哥成年人中,往往超重或肥胖,一般肥胖指标比中心肥胖测量指标作为血压更强的独立预测因素,并不受阈值的影响。

原始出处:

Louisa Gnatiuc, et al. Adiposity and Blood Pressure in 110 000 Mexican Adults. Hypertension. 2017.   https://doi.org/10.1161/HYPERTENSIONAHA.116.08791

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    2017-03-10 feather89
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    2017-02-25 日苒

    代谢综合征

    0

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    2017-02-22 Anima

    肥胖

    0

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    2017-02-22 明月清辉

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