Clin Oral Invest:口腔癌放疗对牙釉质显微硬度及压痕形态的影响

2018-04-27 MedSci MedSci原创

本研究的目的是确定体内外高剂量放疗对釉质显微硬度和相关压痕形态的影响。

本研究的目的是确定体内外高剂量放疗对釉质显微硬度和相关压痕形态的影响。

实验设立三个组评估釉质的内部,中部和外部显微硬度:对照(无辐射);体外照射;体内照射。体外标本用于模拟放射治疗,体内标本来自口腔癌患者放疗后拔除的牙齿。通过SEM图像测量压痕,以计算显微硬度值,并评估放疗前后牙釉质的机械形态学特性。

结果:与对照组相比,釉质的中间和外部区域在体外和体内照射后硬度显着降低(p <0.05)。一共观察到两种压痕模式:模式A-压痕边缘周围存在微裂纹,表示局部变形能耗散;模式B-清洁,锐利的凹痕。与对照相比,在所有釉质区中,体外和体内照射之后,清洁显微压痕模式的百分比显着更高。体内照射组中,在釉牙本质连接处附近的釉质内部区域清洁显微压痕(65%)比例最高。

结论:这项研究首次显示体外和体内照射会改变釉质显微硬度。同样,压痕图案差异表明,釉质在体外和体内照射后可能变得更脆。

原始出处:

R. Seyedmahmoud, et al. Oral cancer radiotherapy affects enamel microhardness and associated indentation pattern morphology.Clinical Oral Investigations. 2018 May. doi:10.1007/s00784-017-2275-z

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    2018-06-18 小几洁
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    2018-04-29 jambiya
  5. [GetPortalCommentsPageByObjectIdResponse(id=1970140, encodeId=e2c319e014016, content=<a href='/topic/show?id=913a59e29c0' target=_blank style='color:#2F92EE;'>#显微硬度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59729, encryptionId=913a59e29c0, topicName=显微硬度)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3289320, createdName=海豹, createdTime=Mon May 14 17:18:00 CST 2018, time=2018-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051138, encodeId=361b20511389b, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Tue Feb 19 04:18:00 CST 2019, time=2019-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020420, encodeId=a4e12020420f5, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Jun 18 15:18:00 CST 2018, time=2018-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568840, encodeId=6a1f1568840be, content=<a href='/topic/show?id=ba256e652dd' target=_blank style='color:#2F92EE;'>#牙釉质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67652, encryptionId=ba256e652dd, topicName=牙釉质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=402115462190, createdName=jambiya, createdTime=Sun Apr 29 14:18:00 CST 2018, time=2018-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309995, encodeId=5fd7309995b6, content=学了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Sat Apr 28 06:54:48 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309969, encodeId=408c309969ea, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRk75KAEKrLGic0S0IvH1aNynsEFQWiaNKdtzvtwj2kafCoPg2icYVbrfBCFiaS74X1uEiaaTTY1H9Xyem/0, createdBy=cec11614828, createdName=chunjianf, createdTime=Sat Apr 28 06:31:07 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309904, encodeId=2897309904bb, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:36 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-28 哈哈869

    学了

    0

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    2018-04-28 chunjianf

    学习了.谢谢分享

    0

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    2018-04-27 wqkm

    ^_^^_^^_^

    0

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