J Hypertens：原发性高血压患者三维超声心动图测得的心室质量/舒张末容积比：每搏输出量与几何形状的关系！

2018-03-26 xing.T MedSci原创

由此可见，在原生高血压患者中，3D超声测得的LVM/EDV比值表明LV向心性几何壁厚的患病率与2D超声相比更高。每搏输出量与LVM/EDV比率呈独立负相关，并且其减少代表了LV向心性几何形状的高血压患者的心肌功能障碍的早期标记。

高血压患者左心室（LV）质量/舒张末期容积比（LVM/EDV）升高与心脏磁共振检查结果上心肌纤维化和功能障碍的证据增加有关。

近日，高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章，研究人员调查了三维（3D）超声心动图根据LVM/EDV比率识别LV向心性几何形状的能力，可能检测到原发性高血压患者的早期心肌损伤。

128例原发性高血压患者接受了二维和三维超声心动图检查。根据在90位健康血压正常的个体的人群中对应于其上限95％置信区间的3D-LVM/EDV比率的截断值，将人群分成两组：LVM/EDV比率截断值在男性中为1.22，在女性为1.23。

与2D衍生的相对壁厚相比，增加的3D-LVM/EDV比值确定了LV向心性几何形状的比率更高（37 vs. 24％，P=0.03）。 LVM/EDV在男性中的比例为1.22或更高，女性中为1.23或更高的患者年龄较大，具有更小的3D-LV舒张末期和收缩末期容积以及更高的LV质量指数，射血分数没有显著差异。LVM/EDV比值升高的患者3D-每搏输出量（P<0.0001）较低。通过多元线性回归分析，调整性别、年龄、心率、平均血压和BMI后，每搏输出量与LVM/EDV比值呈独立负相关（β=-0.55，P<0.0001）。

由此可见，在原生高血压患者中，3D超声测得的LVM/EDV比值表明LV向心性几何壁厚的患病率与2D超声相比更高。每搏输出量与LVM/EDV比率呈独立负相关，并且其减少代表了LV向心性几何形状的高血压患者的心肌功能障碍的早期标记。

原始出处：

Lembo, Maria,et al.Three-dimensional echocardiographic ventricular mass/end-diastolic volume ratio in native hypertensive patients: relation between stroke volume and geometry.Journal of Hypertension. 2018. https://journals.lww.com/jhypertension/Abstract/publishahead/Three_dimensional_echocardiographic_ventricular.97507.aspx

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2018-08-05 feather89

#PE#

20 0
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2018-05-15 zhu_jun9845

#心动图#

31 0
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2019-02-15 ZGMFX24A

#原发性高血压#

53 0
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2018-03-28 虈亣靌

学习了.谢谢作者分享!

64 0
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2018-03-28 维他命

#高血压患者#

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2018-03-27 lietome2

不错的方式.努力学习.刻苦专研.不断总结出来新经验.给点个赞!

52 0
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2018-03-26 戒馋，懒，贪

谢谢分享学习了

57 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Mar 28 19:17:06 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448239, encodeId=a4ca1448239da, content=<a href='/topic/show?id=5a9c102681f2' target=_blank style='color:#2F92EE;'>#高血压患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102681, encryptionId=5a9c102681f2, topicName=高血压患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4665409655, createdName=维他命, createdTime=Wed Mar 28 02:17:00 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300056, encodeId=2c9b300056a4, content=不错的方式.努力学习.刻苦专研.不断总结出来新经验.给点个赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Tue Mar 27 06:11:13 CST 2018, time=2018-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299872, encodeId=dfbc2998e228, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋，懒，贪, createdTime=Mon Mar 26 11:50:43 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299859, encodeId=1e41299859c0, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Mar 26 11:32:47 CST 2018, time=2018-03-26, status=1, ipAttribution=)]
2018-03-26 清风拂面

谢谢分享学习

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