JAHA:轮班工作与高血压患者的心脏代谢性多发病风险

2022-09-02 MedSci原创 MedSci原创

该研究的结果表明夜班工作与高血压患者较高的心脏代谢性多发病风险相关。

心脏代谢多病的定义是2种及以上心脏代谢疾病共存,其已成为公共卫生专业人员的新兴研究重点。尽管轮班工作与个体心脏代谢疾病之间的关系已经得到了充分的研究,但其在心脏代谢性多发病进展中的作用尚不清楚。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员探讨了轮班工作与高血压患者心脏代谢性多发病发生率之间的关系。

该研究是一项基于人群的前瞻性队列研究,涉及36939名英国生物库参与者。研究人员使用竞争风险模型来评估轮班工作与心脏代谢性多发病风险之间的关联,心脏代谢性多发病在研究人员的研究中被定义为高血压和糖尿病、冠心病或卒中合并症。研究人员还调查了轮班工作的频率和持续时间与三坐标测量机风险之间的关联。此外,研究人员进行了交叉分类分析,结合轮班工作频率和时间、睡眠类型和睡眠时间作为暴露指标。

在中位11.6年的随访中,共有5935名参与者发生了心脏代谢性多发病。研究人员发现,通常/总是夜班的工人与白班工人相比,心脏代谢性多发病的风险高16%(风险比为1.16[95%CI为1.02-1.31])。研究人员还发现,高频率的夜间轮班(>10/月)与心脏代谢性多发病风险增加相关(风险比为1.19[95%CI为1.06-1.34]),在10个月以上的夜班工作者与早晨睡眠类型或睡眠时间相结合<7小时或>8小时的工人中更明显(风险比为1.26[95%CI为1.02-1.56];风险比为1.43[95%CI为1.19-1.72])。

由此可见,该研究的结果表明夜班工作与高血压患者较高的心脏代谢性多发病风险相关。

原始出处:

Liu Yang.et al.Shift Work and the Risk of Cardiometabolic Multimorbidity Among Patients With Hypertension: A Prospective Cohort Study of UK Biobank.JAHA.2022.https://www.ahajournals.org/doi/full/10.1161/JAHA.122.025936

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    2023-03-12 sodoo
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    2022-09-04 zhaohui6731
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