Gastroenterology:有组织的计划性结肠癌筛查可大幅降低结肠癌发病率及死亡率

2018-07-20 zhangfan MedSci原创

研究认为,由政府主导有组织的结肠癌筛查计划可大幅降低结肠癌发病率,降低终末期肿瘤发病率及死亡率

近日研究人员就有组织的计划性结直肠癌(CRC)筛查对社区人群筛查参与率、发病率和死亡率的影响进行了考察。

2007-08年间加拿大奥克兰地区开始实施计划性有组织的年度粪便免疫化学检查和结肠镜结肠癌筛查计划,参与人群为51-75岁居民。研究人员考察2000年前以及2015年后社区人口结肠癌筛查参与率、患病率以及死亡率的变化。

有组织的CRC筛查计划大幅提高社区居民结肠癌筛查参与率,由2000年的38.9%上升至2015年的82.7%。2000-15年间,年度结肠癌发病率下降了25.5%,由每100000患者95.8例下降至71.4例;肿瘤特异性死亡率下降了52.4%,由每100000患者30.9例下降至14.7例。筛查开始后,结肠癌发病率增加,其原因是早期肿瘤的检出率大幅增加,随后肿瘤事件率呈现出下降的趋势。有组织的结肠癌筛查效果十分显著,晚期CRC发生率下降36.2%,由每100000患者45.9例下降至29.3例;早期CRC发生率下降14.5%,由每100000患者48.2例下降至41.2例。

研究认为,由政府主导有组织的结肠癌筛查计划可大幅降低结肠癌发病率,降低终末期肿瘤发病率及死亡率。

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time=2018-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333102, encodeId=6a20333102e5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Jul 21 08:09:53 CST 2018, time=2018-07-21, status=1, ipAttribution=)]
    2018-08-26 许安
  5. 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  6. 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  7. 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time=2018-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333102, encodeId=6a20333102e5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Jul 21 08:09:53 CST 2018, time=2018-07-21, status=1, ipAttribution=)]
    2018-07-22 窦效由 窦药师

    学习学习学习

    0

  8. 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href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Sat Jul 21 21:33:00 CST 2018, time=2018-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333106, encodeId=5afe33310604, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Sat Jul 21 08:14:20 CST 2018, time=2018-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333102, encodeId=6a20333102e5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Jul 21 08:09:53 CST 2018, time=2018-07-21, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=1799848, encodeId=54a41e998481c, content=<a href='/topic/show?id=9e3fe127909' target=_blank style='color:#2F92EE;'>#癌发病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71279, encryptionId=9e3fe127909, topicName=癌发病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2c92500045, createdName=12498636m49(暂无昵称), createdTime=Thu Feb 14 04:33:00 CST 2019, time=2019-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823477, encodeId=bf9e18234e78e, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, 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href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Sat Jul 21 21:33:00 CST 2018, time=2018-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333106, encodeId=5afe33310604, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Sat Jul 21 08:14:20 CST 2018, time=2018-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333102, encodeId=6a20333102e5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Jul 21 08:09:53 CST 2018, time=2018-07-21, status=1, ipAttribution=)]
    2018-07-21 神功盖世

    学习

    0

  10. 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time=2018-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333102, encodeId=6a20333102e5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Jul 21 08:09:53 CST 2018, time=2018-07-21, status=1, ipAttribution=)]
    2018-07-21 sunfeifeiyang

    学习

    0

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