Sci Rep: 乡村和城市环境中的儿童和青少年皮肤微生物群模式是不同的

2017-04-27 AlexYang MedSci原创

人类微生物群的组成收到多种因素的影响。理解微生物群的动态对提高人类健康水平是重要的,因为微生物在炎症疾病中的发生有着关键的角色,比如过敏性疾病过敏性鼻炎等。最近,研究人员研究了住在不同环境中275名芬尼斯孩子(几个月大到青少年)双臂的皮肤微生物群。研究人员发现,尽管年龄是一个主要影响皮肤微生物构成的因子,生活环境同样能够区别化城市和乡村孩子的皮肤微生物群。并且,环境的影响具有年龄特异性,在刚学步的

人类微生物群的组成收到多种因素的影响。理解微生物群的动态对提高人类健康水平是重要的,因为微生物在炎症疾病中的发生有着关键的角色,比如过敏性疾病过敏性鼻炎等。

最近,研究人员研究了住在不同环境中275名芬尼斯孩子(几个月大到青少年)双臂的皮肤微生物群。研究人员发现,尽管年龄是一个主要影响皮肤微生物构成的因子,生活环境同样能够区别化城市和乡村孩子的皮肤微生物群。并且,环境的影响具有年龄特异性,在刚学步的孩子中最为明显,在新生儿中不明显,而在青少年中不存在。个人的变化同样与年龄和环境相关。令人惊讶的是,手臂微生物群的变化在乡村中除了青少年之外,其他年龄段的变化较小。研究人员同样收集了血清样本对变应性致敏进行鉴定,结果发现了变应性致敏与微生物构成的一个较弱的但是显着的相关性。最后,研究人员指出,身体的和行为的变化,以及年龄和对环境微生物接触量可以共同影响皮肤微生物群的动态变化,并且也解释了在青少年中皮肤微生物群与生活环境的相关性丢失的原因。

原始出处:

Jenni Lehtimäki, Antti Karkman, Tiina Laatikainen et al. Patterns in the skin microbiota differ in children and teenagers between rural and urban environments. Sci Rep. 31 March 2017. doi:10.1038/srep45651

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    2017-04-29 虈亣靌

    不错的方式,努力学习,刻苦专研,不断总结出来新经验。

    0

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    2017-04-29 虈亣靌

    不错的方式,努力学习,刻苦专研,不断总结出来新经验。

    0

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