Stroke:颈动脉血管成形术后,颈动脉再狭窄的预测因子

2016-06-29 phylis 译 MedSci原创

背景:颈动脉血管成形术(有或无支架)后再狭窄与卒中和死亡发生率增加有关。研究者旨在确定颈动脉血管成形术颈动脉再狭窄及与再发性脑血管事件相关的危险因素和预测因子。方法:在一所大学医院(从2002至2013),所有颈动脉狭窄患者的进行血管成形术(n = 1060)治疗。进行随访前瞻性评估再狭窄,同侧脑卒中或死亡。再狭窄的定义为:血管超声显示狭窄的≥治疗前的70%。结果:治疗的1060例患者中,在随访过

背景:颈动脉血管成形术(有或无支架)后再狭窄与卒中和死亡发生率增加有关。研究者旨在确定颈动脉血管成形术颈动脉再狭窄及与再发性脑血管事件相关的危险因素和预测因子。

方法:在一所大学医院(从2002至2013),所有颈动脉狭窄患者的进行血管成形术(n = 1060)治疗。进行随访前瞻性评估再狭窄,同侧脑卒中或死亡。再狭窄的定义为:血管超声显示狭窄的≥治疗前的70%。

结果:治疗的1060例患者中,在随访过程中,9.2%(97)的患者出现再狭窄(中位数为12个月[ 9-32 ])。随访期间再狭窄发生与同侧脑卒中发生相关(P = 0.049)。Cox回归分析后,高血压(HR,6.2 [ 1.9-19.9 ]),受损的血管反应性(HR,1.7 [ 1.09-2.8 ]),和无支架血管成形术(HR,2.9 [ 1.2-6.8 ];P = 0.012)是> 70%再狭窄的独立危险因素。

结论:颈动脉血管成形术后颈动脉再狭窄与同侧脑卒中的发生相关。在研究样本中,高血压,无支架血管成形术,和受损的血管反应性可识别颈动脉再狭窄高危患者,随访中超声成像有助于选择患者。

原始出处:

Zapata-Arriaza E, Moniche F, et al. Predictors of Restenosis Following Carotid Angioplasty and Stenting. Stroke. 2016 Jun 21


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    2016-10-11 ylzr123

    好文值得点赞!继续关注学习。

    0

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